Noopept is a powerful nootropic supplement which is a derivative of the racetam drug family. Many people consider Noopept nootropic drug as among the best cognitive enhancers. Besides, it is a go-to supplement for the people looking for supplements with neuroprotective properties. Although it has dipeptide structure, similarly to Piracetam, the strength of Noopept is different from that of Piracetam.
In this Noopept review, we are going to see the Noopept background, Noopept nootropic stack, Noopept side effects, Noopept vs Piracetam comparison, Noopept dosage and Noopept benefits and the best place to buy Noopept (GVS-111) powder.
Noopept 157115-85-0 was manufactured for the first time in 1996 and since then, it has been of great help to people. It is mostly prescribed as a treatment for different cognitive disorders such as traumatic brain injury, cognitive deterioration due to old age and cerebral vascular insufficiency. The supplement remains unregulated in many countries and states, and so, it is easily accessible, especially with the online market.
Although currently there’s no documented study about the cognitive enhancing capability of Noopept (GVS-111) powder on a healthy person, anecdotal reports from the users of Noopept nootropic show positive nootropic effects of the supplement.
Just like other nootropic drugs, Noopept powder is a smart drug which if taken by a healthy person, it can improve his or her mental performance. However, unlike the natural nootropics, Noopept is a synthetic supplement and its effects are felt faster as compared to the natural nootropics.
The effects of Noopept are normally felt within a couple of minutes after taking it while other nootropics (especially the natural ones) might take hours or days.
The metabolism of Noopept nootropico takes place in the liver after which, the digestive system absorbs the drug rapidly. Then the supplement spreads quickly, reaching the entire blood stream and even the brain.
It’s not yet quite clear how Noopept actually works. However, it seems like the effects of Noopept psychonaut exhibit when the supplement works in the brain in various ways. First, it’s believed that Noopept increases the acetylcholine’s neural response by imparting a sensitizing effect on the processes of the neurotransmitter.
Since acetylcholine remarkably influences the learning and cognition abilities of a person, Noopept, therefore, Noopept helps in boosting the levels of the two.
Also, research shows that Noopept nootropic boosts the expression of Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). The two neurotrophin proteins (NGF and BDNF) are very important not only in memory health but also cognition as well. They regulate the excitatory neurotransmitter glutamate’s brain levels.
By modulating the activity of both receptors, Noopept helps in the prevention of the toxicity of glutamate, which could damage neurons. The supplement also helps in the elimination of excess calcium and improves the flow of blood.
Besides, through calcium and glutamate levels, the nootropic also improves neuroplasticity which is very helpful in long-term memory formation. The effect of the nootropic also leads to improved blood flow by boosting brain health and improving the composition of blood.
When comparing Noopept vs Piracetam, there are some similarities and differences between the two. The effects of Noopept are similar to Piracetam’s and the two also share some similarity in terms of their mechanisms.
Both nootropics provides stimulating effect and help in anxiety reduction and offer remarkable neuroprotection. Besides, they are used to improve human cognition. As such they are used for learning and Memory improvement. Again, both drugs are soluble in water
However, the chemical structure of Piracetam differs from that of Noopept because the latter isn’t not exactly a Racetam, unlike Piracetam. As such, the major difference as far as Noopept vs Piracetam is concerned occurs in their respective strengths as well as action speed.
Noopept is about 1,000 times stronger as compared to Piracetam and so, its absorption by the body is faster. That’s why a Noopept vendor will tell you that the drug is 1000-times more effective than Piracetam. While the standard Noopept dosage ranges from 10 mg to 30 mg per day that of Piracetam is 3000 mg to 4000 mg.
That’s why many Noopept reddit reviews indicate that lots of users experience the effect of Noopept within an hour or a few minutes of taking the supplement while those who take Piracetam have to wait for a hours before experiencing the Piracetam effects.
Furthermore, Noopept the effects of Noopept last longer than those of Piracetam. Another difference is that the adverse psych stimulatory Noopept effects are fewer than those caused by Piracetam.
Another difference: unlike Piracetam which exclusively facilitates the memory process’ initial stages, Noopept powder intake influences the steps that involve the consolidation and retrieval of memory. Therefore, unlike Piracetam which only helps one to develop memory, Noopept goes an extra mile to help you regain the memory and recall the information stored in your memory.
Also, Noopept has an additional benefit of anti-anxiety action, which lacks in Piracetam. Nooptet’s ability to relief anxiety is attributed to its antioxidant effect, ability to bar potentially toxic excess calcium and glutamate as well as due to its anti-inflammatory action
The information provided by the manufacturer and various Noopept reddit reviews, Noopept is used for various purposes. The major Noopept benefits include:
The effects on memory are backed up by the research conducted in models where there’s reduced cognitive ability or damaged brain. In all such cases, most of which have been conducted in Russia, it’s been proved that Noopept boosts memory health.
Specifically, the supplement have been found to be an effective treatment for different cognitive disorders such as neurodegeneration due to old age, brain damage as a result of alcohol use, stroke and organic brain disease.
On various studies conducted on animals to establish the Noopept effects, particularly the ability of the drug to improve cognition, the researchers noted that the supplement stimulated NGF and BDNF. Both chemicals play a vital role in human’s cognition power.
With the right NGF level, the body is able to produce new nerve cells in a process known as neurogenesis. When the body produces enough nerve cells, the brain’s neural networks perform better in all areas associated with cognition.
On the contrary, when the NGF level is low, perhaps due to bipolar disorder, dementia, Rett syndrome, schizophrenia or Alzheimer’s disease, among other brain-related disorders, the body is unable to achieve the healthy neurogenesis level. As a result, the performance of the neural networks within the brain deteriorates.
Noopept can be of great help for people with poor brain health as a result of low NGF level due to low nerve cells. The drug boosts NGF level, making the body to produce more cells. Besides, Noopept 157115-85-0 leads to a higher survival rate and period of the nerve cells which include brain cells.
The drug acts in each memory processing phase, by stimulating BDNF, to improve your memory. BDNF, just like NGF, influences the generation of nerve cells, but this deals with the nerve cells found in the brain areas that are closely associated with learning, higher thinking as well as memory.
With stimulated BDNF as a result of Noopept, a person develops better short-term and long-term memory. Therefore, if you are worried about your poor memory, Noopept could be of great help to you.
People who struggle to maintain focus can also benefit big time from Noopept high Neuroprotective properties which are helpful for brain health. The properties boost your brain’s functioning in such a way that helps you to focus better for extended periods.
Noopept can also boost your learning capability. When the drug energizes the neurotransmitter in the brain, it contributes to improved neural network communication. The more effective NGF and BDNF as a result of Noopept effects leads to a higher survival rate of the existing neurons and improved synapse and neuron growth.
The effects are most prevalent in the hippocampus as well as the cerebral cortex. The two brain areas mostly influence your thinking and learning abilities. Consequently, you gain some mental fatigue relief and are able to process information and learn quickly.
Noopept can also Reduce anxiety in a person. The studies conducted on animals to establish the ability of the Noopept to reduce anxiety, the researchers noted that the animals that has been treated with the drug had considerably lower levels of anxiety that their counterpart who didn’t receive the treatment.
In another research done on people suffering from mild cognitive disorders, a Noopept dosage of 10mg times a day lead to anxiety reduction. However, in Noopept reddit reviews, some users of the supplement report anxiety relief after taking the supplement while others say they experienced more anxiety.
For those who feel less anxious after using noopept, it’s suspected that the drug stimulates the brain areas where dopamine and nicotinic receptors are found, consequently leading to reduced anxiety. Besides, in many people, the supplement stimulates particular serotonin receptors. The receptors are responsible for mood regulation. Therefore, if stimulated, they make you to feel happier.
Improved sensory perception is also among the Noopept benefits. Besides having improved brain health and cognitive ability, some people who take Noopept nootropic also report improved sensory perception as a result of the drug. For instance, they experience better vision and hearing ability after using the supplement.
It’s because of this effect that many Noopept users report that they appreciate music better following the use of the drug. They say that they find music sounding richer and fuller as a result of using the supplement.
Now, coming to Noopept powder how to take the drug. Well, the typical Noopept powder dosage is 10 milligrams. The drug in that amount is supposed to be taken two times every day and should be preceded by a meal. This is the recommended dose for a start.
However, if need be, the Noopept dosage can be adjusted upwards to about 30mg per day; that’s about two 15mg doses in a day. However, some of the people who use the drug report that higher Noopept powder dosage reduces the cognitive effects that they expect from it.
Normally, the use of Noopept is prescribed to duration of one and a half to three months. If the desired results aren’t achieved during the course of treatment, another cycle of the same period can be prescribed again. However, the second course should be started at least a month after the end of the first one. Taking Noopept in cycles prevents tolerance.
If you want to maintain a healthy sleep pattern, try as much as you can to avoid taking Noopept late in the evening. This is because the fresh effects of the drug might interfere with your sleep.
Noopept is among the most effective Cognitive enhancers and so, you can get the desired effects even when you use it alone. However, if you want stronger effect, a Noopept nootropic stack featuring other supplements, including nootropics could of more benefit. Some of the nootropics that are commonly included in a Noopept nootropic stack are Piracetam, Alpha GPC and Aniracetam.
A study that was done to establish the compatibility and effectiveness of a noopept-Piracetam showed a combination of the two nootropics lead to improved brain blood vessel functionality in humans. As such, the stack can be of great help for people suffering from mild cognitive disorders.
Staking 10 milligrams of Noopept with 2 grams of Piracetam will improve the effectiveness of your neurotransmitters significantly, and better than when you use either of the two drugs independently. If want the Piracetam effect more pronounced, you can add a choline supplement such as Alpha GPC. For Alpha GPC, incorporate 300mg of it in the package.
In case you want to have a better mood, anxiety relief and better memory, consider stacking 10 milligrams of Noopept with one gram of Aniracetam. The latter will boost the noopept’s ability to decrease anxiety. For creativity improvement, adding add 300 milligrams of Sulbutiamine to the combo will be a good idea. Add 300 milligrams of Alpha GPC to the mixture if you want it to be more potent.
Although generally Noopept is regarded as safe and with good tolerance, it has a few minor side effects. Some of the most common Noopept side effects include:
The above Noopept side effects mostly occur when the drug is taken in higher dosages than the recommended amount.
However, even in minute quantities, Noopept doesn’t go well with people with hypertension as it can increase their blood pressure to unhealthy levels. Besides, it is advisable for those with depressive disorders to stay away from the drug because it could worsen their depressive symptoms.
Although not quite common, other Noopept side effects include random and meaningless thoughts¸ tingling sensations and relaxation-induced anxiety
To avoid these among other adverse Noopept effects, pregnant/lactating women, individuals with lactose intolerance and those suffering from liver or kidney malfunction shouldn’t use the Noopept
Just like other Nootropics, the legal status of Noopept differs from one country to another worldwide. Nevertheless, the drug is unregulated in most countries, including the U.S, Brazil, UK, Canada and Australia.
Noopept FDA status doesn’t yet confirm the effectives of the drug in offering the aforementioned benefits. Because of that, in the U.S, Noopept isn’t allowed to be advertised as a medicine for human use. Instead, it is sold as a general supplement until when Noopept FDA research will come out with absolute confirmation.
Where Noopept buy and use isn’t regulated, one can make a Noopept buy offline or online without being asked to submit doctor’s prescription. However, it’s important for you to ensure that it’s from the best Noopept supplier to avoid buying contraband. Besides, because of the lack of doctor’s prescription, one should use it in the recommended dosage to avoid undesired effects.
Are you wondering where to get Noopept powder for sale? Don’t worry; access to the product shouldn’t be a hassle. You can make Noopept powder buy effortlessly from wisepowder.com, the best Noopept supplier.
Although there are lots of options for Noopept online buy, you shouldn’t trust just anyone who or any company which claims to be the best Noopept supplier. Remember that scammers and counterfeit sellers have their share in the online world.
However, rest assured that you can’t go wrong at all with a trusted Noopept vendor like wisepowder.com. It’s a very reliable and convenient place for a fast and genuine and pocket-friendly Noopept online buy.
From this Noopept nootropics review, we’ve seen that Noopept is among the most effective cognitive enhancers which are also known as smart drugs. However, before you thing of making a Noopept buy, you need to know if the drug is regulated in your country or not. Where it is not regulated, you can buy it as a general supplement which doesn’t require any doctor’s prescription to acquire or use it.
Although the Noopept psychonaut benefits are many and quite desirable, the recommended use of the drug should be adhered to. Otherwise, taking an overdose of Noopept nootropico can lead to some minor Noopept side effects such as headache, fatigue, nausea and irritability.
Whether you want Noopept powder (157115-85-0) for sale or Noopept nootropico for your own consumption, wisepowder.com is the best Noopept vendor to count on for a genuine Noopept powder buy.
Co-founder, the company’s core administration leadership; PhD received from Fudan University in organic chemistry. More than nine years of experience in organic synthesis field of medicinal chemistry. Rich experience in combinatorial chemistry, medicinal chemistry and custom synthesis and project management.
Ostrovskaia, R. U., Gudasheva, T. A., Voronina, T. A., & Seredenin, S. B. (2002). The original novel nootropic and neuroprotective agent Noopept. Eksperimental’naia i klinicheskaia farmakologiia, 65(5), 66-72.
Ostrovskaya, R. U., Gruden, M. A., Bobkova, N. A., Sewell, R. D., Gudasheva, T. A., Samokhin, A. N., … & Morozova-Roche, L. A. (2007). The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer’s disease model. Journal of psychopharmacology, 21(6), 611-619.
Jia, X., Gharibyan, A. L., Öhman, A., Liu, Y., Olofsson, A., & Morozova-Roche, L. A. (2011). Neuroprotective and nootropic drug Noopept rescues α-synuclein amyloid cytotoxicity. Journal of molecular biology, 414(5), 699-712.
Kondratenko, R. V., Derevyagin, V. I., & Skrebitsky, V. G. (2010). Novel nootropic dipeptide Noopept increases inhibitory synaptic transmission in CA1 pyramidal cells. Neuroscience letters, 476(2), 70-73.
Ostrovskaya, R. U., Vakhitova, Y. V., Kuzmina, U. S., Salimgareeva, M. K., Zainullina, L. F., Gudasheva, T. A., … & Seredenin, S. B. (2014). Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. Journal of biomedical science, 21(1), 74.
Is there a person I can talk to who knows more about the safety of Noopept than what Google is able to provide?
A note about Noopept. I’ve tried this substance 4 times— once one day, twice in one day on another day, and once the day after— and have developed the occasional headache after I stopped taking it completely. (maybe as a consequence of even trying it) I’ve looked through the internet time and time again for a solid answer but it doesn’t seem like I’m going to get one any time soon.
My main question would be its potential side effects on the developing individual, particularly a 20 year old such as myself. Is there anyone I could talk to, whether DM or even over the phone who would have a substantial field of knowledge in research and maybe neuroscience who can help alleviate my worry’s about Noopepts potential long term damage or long term effects? I could add 20 paragraphs worth of more information about my past and history but I’d rather keep this short. Thank you. -Michael
How long does Noopept stay in the system?
I am planning on tripping but I am currently using Noopept. From my “research” (extensive google searching) it seems that Noopept potentiates LSD.
I am not trying to potentiate my trip so my question is: Does anyone know how long Noopept stays in the system? (Preferable someone with experience on this)