Best Nootropic Stack Guide: Everything You Need To Know [5 Years Experience]
Did you know that you could become smarter without having to burn the night lamp studying? If there was a powder that could help you improve your memory or increase your wakefulness, would you take it?
Today, smart drugs, also known as nootropics, are becoming a darling to many. The reason for this is because they are known to better one’s day to day life. The nootropic benefits range from prolonged spans of attention, more concentration, increased focus as well as a vigilant brain.
You will notice that there are students who are not very good at remembering and will want to ace their exam without much struggle. Also, there are people with high-status jobs with high stakes who would want to maintain high concentration all day.
On top of that, some people use nootropics and smart drugs powder to manage motor function disorders like Alzheimer’s, Hunnington disease, Parkinson, and ADHD. It is for such reasons that you may consider using nootropics to stay ahead of the rest.
In this piece, we have narrowed down the top 15 nootropic powders and what makes them stand out.
Understanding the different types nootropics
In the recent past, the smart drugs industry has grown, with more nootropics becoming available than ever before. Here are the six categories that nootropics can be classified into;
These are some of the widely used cognitive enhancers that are sold over the counter. What’s good about them is the fact that they improve one’s cognitive function without acting like a stimulant or a sedative. Although scientists have not yet understood their mechanism of action fully, it is said that they increase blood flow and oxygen consumption is some parts of the brain.
Fortunately, they are easily accessible as you can readily find them online. Also, very few cases of side effects have been reported so far.
Usually, most of the drugs in this class work well when used over prolonged periods. That means that to enjoy the peak benefits, you have to use it for several weeks.
Any nootropic considered to be herbal, organic, or natural belongs to this class. Often, they are usually plant-based and give natural benefits. This class of drugs is frequently preferred because they are safe to use as they do not contain artificial compounds or chemicals.
One of the main shortcomings is that they do not pack a punch as compared to synthetic nootropics. One may, therefore, need to take very high doses to get the same effect as that of synthetic ones.
Vitamin B derivatives
Just like the name suggests, Vitamin B derivatives are nootropics derived from B Vitamins to extract the best benefits. They affect the glutamate, choline, and dopamine levels in the brain, and this makes them useful in the treatment of degenerative cognitive disorders such as ADHD.
Ultimately, these derivatives are used in the treatment of physical and mental fatigue as well as in the improvement in memory retention.
You have probably learned about peptides in the past. They are naturally occurring biological molecules made of amino acids and that are linked by covalent chemical bonds. Although they are not easily accessible, Noopept is available online and in stores. Peptides are strong and have shown to improve motivation, memory, mental energy, learning capabilities, and alertness.
Choline is naturally found in the body, but we might sometimes suffer from its deficiency. Consequently, this leads to reduced cognitive abilities hence a reduction in the overall wellbeing of the brain. Taking choline nootropics help in increasing the brain’s production of acetylcholine neurotransmitters.
Choline supplements can either be taken on their own or together with racetams. When stacked together, they lead to increased memory, learning capabilities, and an improvement in the overall mood.
The ampakines are some of the most potent nootropics that were introduced recently. They work through the stimulation of the glutamate receptors in the brain. As a result, they lead to increased levels of glutamate, which in turn improves learning and memory.
|Best overall nootropic powder:||Best nootropic for memory improvement:||Best nootropic for athletic performance:|
|Purity≥98% Flmodafinil powder |
|Purity≥98% Pramiracetam Powder |
|Purity≥98% Carphedon powder |
|Why we piced it: ||Why we piced it: ||Why we picked it: |
|Check Price More Details||Check Price More Details||Check Price More Details|
|Here Are The Top 15 Nootropics Smart Drug Powder: |
Best overall nootropic powder-Flmodafinil powder
Best nootropic for wakefulness- Adrafinil Powder
Best intelligence enhancer- Fladrafinil(CRL-40,941) Powder
Compare the best 15 smart drug nootropic powders in 2019
|NAME||RATING||SIDE EFFECTS||RECOMMENDED DOSAGE||HALF-LIFE|
|Flmodafinil powder||5||Very few||100-200mg per day||12-15 hours|
|Pramiracetam powder||5||Very few||600-1200mg per day||5-6 hours|
|Carphedon powder||5||Few||200-750mg per day||3-5 hours|
|Adrafinil powder||4.5||Few||600-900mg per day||12-15 hours|
|Fladrafinil powder||5||Little to no side effects||100-200mg per day||6-7 hours|
|Hydrafinil powder||4.5||Few||50-150mg per day||6-8 hours|
|Noopept popwder||5||Few||30-60mg per day||3-6 hours|
|Nefiracetam powder||4.5||Very few||600-900mg per||3-5 hours|
|Aniracetam powder||5||Few||1500mg||1-2.5 hours|
|J-147 powder||5||Several||20-30mg||1.5-2.5 hours|
|Magnesium L-Threonate powder||5||Few||1500-2000mg||44 hours|
|Nicotinamide Riboside Chloride powder||4.5||Very few||1000-2000mg||5.3 hours|
|Galantamine Hydrobromide powder||4||several||4-8mg||7 hours|
|7P powder||5||Few||5000mg||1-2 hours|
|N-Acetyl-L-cysteine ethyl ester powder||4.5||Few||5000mg||5.6 hours|
| Best overall nootropic powder |
1. Purity≥98% Flmodafinil(CRL-40,940) powder 90280-13-0<
For someone looking for a very effective nootropic without pumping too much of it into the system, then the Flmodafinil powder is the real deal. It is a joy to use since the Flmodafinil dose needed is 100-200mg divided twice daily. From the Flmodafinil reviews given by the users, it is evident that this nootropic will make you feel and think like a boss by just taking a small amount of it.
It has proven to increase one’s cognitive ability and productivity by increasing the amount of histamine, orexin, glutamate, and norepinephrine levels. Other than that it also works by inhibiting the breakdown of dopamine in the body.
Secondly, it aids in the treatment of minor depression through the restoration of one’s regular mood. It also assists in the management of ADHD and other conditions that are attention-related. Additionally, Flmodafinil is known to increase wakefulness, improve motivation, and focus, and even better one’s mental performance.
When comparing Flmodafinil vs. modafinil, several features that come into count, for instance, the Flmodafinil side effects are very few compared to those of modafinil. Although they appear to be the same thing, their structural formula is quite different, and this makes Flmodafinil more bioavailable.
If you are wondering where to buy Flmodafinil powder, then you shouldn’t look any further. You could opt to buy Flmodafinil online for as a more convenient and cheaper option. We are the legit nootropic powders source where you can buy CRL-40,940 Flmodafinil powder.
- It works by altering the histamine, orexin, dopamine, glutamate, and norepinephrine levels.
- The recommended dosage is 100-200mg per day.
- It has been tested on animals.
| Best nootropic for memory improvement |
Whether you are a learner looking to do their final exams or a senior who wants to preserve their grey matter, then pramiracetam is for you. It is the best nootropic when it comes to maintaining a strong memory. Pramiracetam belongs to the racetam family but is thirty times stronger than the racetams.
Pramiracetam powder works by increasing the rate of choline uptake and Nitric oxide production in the brain. The main Pramiracetam benefits include; improvement in focus and recovery from any brain injuries. It also helps in the reversal and prevention of amnesia.
The Pramiracetam stack often contains a choline source to counter the reduced acetylcholine levels in the brain and improve the cognitive function. It could also be stacked with Adrafinil, Armodafinil, and Modafinil. Comparing Pramiracetam vs. Phenylpiracetam, it is clear that Pramiracetam does not cause side effects like irritability, nausea, and headaches like the latter.
If planning to buy Pramiracetam in retail or bulk powder, then you can always count on us.
- It has a fast onset of action.
- Provides psycho stimulation without leading to hyperstimulation.
- The duration of treatment is short.
- It is fat-soluble hence best taken together with meals.
| Best nootropic for athletic performance |
Carphedon is a piracetam derivative whose only physical difference with piracetam is the phenyl group attached to it. Due to this group, the phenylpiracetam powder dosage needed to give the same effect as Piracetam is lower and is considered to be 20-60 times more powerful than Piracetam.
Most of the Phenylpiracetam reviews rave about its efficacy in boosting athletic performance due to the stimulatory effects it gives. It also helps people resist cold. Other benefits include the management of epilepsy, stroke, memory disorders, and fatigue.
Phenylpiracetam should not be taken during bedtime as it could lead to sleep disturbances. Also, you should take it two to four times a week or in cycles to prevent the body from building a tolerance to the stimulating effect.
- It has a fast onset of action.
- Provides psycho stimulation without leading to hyperstimulation.
- The duration of treatment is short.
- It is fat-soluble hence best taken together with meals.
| Best nootropic for wakefulness |
4 Purity≥98% Adrafinil Powder 63547-13-7
If your objective is to increase wakefulness and decrease sleepiness, then you should consider taking adrafinil powder. Majority of the Adrafinil reviews show that it is instrumental in helping one stay awake for more extended periods. In terms of the Adrafinil Vs. Modafinil half-life, the latter has a longer one. Adrafinil however gets converted into modafinil while in the body adding on its half-life hence longer-lasting effects.
Other Adrafinil effects include increasing focus; improving one’s learning capacity and supporting memory. Although it could cause a few side effects, it is considered to be a safe stimulant since it does not cause most of the unpleasant side effects associated with stimulants.
It is best taken with water or citrus juice due to the bitter Adrafinil powder taste. Since it is legal in most of the countries, you can buy adrafinil powder online without the need of a prescription.
- The recommended dosage is about 600-900mg.
- The Adrafinil effectslast for 12-15 hours.
- It should not be taken daily or for an extended period as it builds a tolerance.
| Best intelligence enhancer |
5 Purity≥98% Fladrafinil (CRL-40,941) Powder 90212-80-9
Are you looking for something that will help you soar to possibilities beyond what you ever dreamt of? Fladrafinil powder is the best drug in increasing one’s mental clarity and capacity. It works by deterring the breakdown of dopamine hence the regulation of emotional responses, learning, and attention.
Fladrafinil is similar to modafinil powder in terms of their composition and effects with the only difference being the extra fluoride molecule. The addition makes Fladrafinil to be readily absorbed into the body.
The Fladrafinil side effects are few, but their severity could increase with constant use. Luckily, it is readily available, and you can buy Fladrafinil online if you want to.
- The Fladrafinil dosageshould be around 100-200 mg in a day.
- The Fladrafinil side effectsoccur rarely.
- It is 3-4 times more potent than Adrafinil and Modafinil.
| Best attentiveness promoter |
Hydrafinil powder, also known as Fluorenol is a dopamine reuptake inhibitor whose main effect is to increase attentiveness. Other Hydrafinil benefits include enhanced mental energy, better concentration, and reduced fatigue.
The Hydrafinil mechanism of action also involves the increase of the histamine, norepinephrine, and glutamate levels to enhance one’s mood. When comparing the Hydrafinil vs. modafinil bioavailability, Hydrafinil nootropic has demonstrated to have a shorter one.
Its sale is unregulated hence you could buy raw Hydrafinil (9-Fluorenol) anytime you want to.
- It is inexpensive compared to other nootropics.
- Hydrafinil is less stimulating hence few adverse reactions.
- The Hydrafinil effectsare thought to be subtle.
| Best fast-acting nootropic |
Noopept powder is a synthetic nootropic widely taken as a supplement. It is the fastest acting smart drug as you are likely to feel its effect within minutes. If you are wondering how Noopept works, then I will tell you how. Its mechanism of action involves an increase in two essential brain chemicals; NGF and BDNF.
The Noopept benefits include an improvement in one’s memory, clarity, speed of thought, focus, positivity, and enthusiasm.
The only notable Noopept side effect is headaches that are a result of taking a high dose or using the Noopept nootropic powder for the first time. The advantage of Noopept is that it is legal and only regulated in a few countries. That means that if you need to buy Noopept, you need to consider your country’s laws. By doing this, you can tell if you need a prescription or not.
- The Noopept dosageis 30-60 mg per day.
- It is very tolerable and comes with minimal side effects.
- It is best stacked with choline.
| Best nootropic for neuroprotection |
After suffering from a stroke, many patients are reported to experience seizures, which could lead to brain damage as well as memory loss. Fortunately, Nefiracetam has proven to protect against seizures. It does this by controlling the NMDA signaling which prevents against the upsurge of the glutamate levels.
It is one of the newer members of the racetam members, and some of its other benefits include the enhancement of mood, learning, and memory. When comparing nefiracetam VS aniracetam, most nefiracetam reviews report that it causes significant improvement to one’s mood.
The Nefiracetam side effects are few, thus considered to be safe and well-tolerated.
- It is a fat-soluble drug; hence, low dosages tend to be more effective when compared to piracetam.
- Nefiracetam has undergone animal studies as well as some human studies.
- The dosage is 100mg-900mg per day, taken twice; one in the early morning and the second in the early afternoon.
| Best mental enhancer |
The smart powder aniracetam is an ampakine nootropic that is more potent than piracetam. It takes the medal when it comes to mental enhancement and works by stimulating the AMPA receptors; the commonest CNS glutamate receptor. AMPA receptors play a significant role in the formation of memories and learning.
Other benefits of Aniracetam powder include an increase in the reflexes, reduction in anxiety, and increase in perception. The fewer side effects it causes when compared to piracetam makes it more popular not to mention its results that are far much stronger than a cup of coffee.
Aniracetam powder heightens one’s brain capacity by increasing the brain-derived neurotrophic factor, which acts as a brain fertilizer.
- It is highly fat-soluble.
- The Aniracetam dosageis 1500mg divided twice in a day.
- One can feel the Aniracetam effect15-20 minutes after taking it.
| The best nootropic in the treatment of Alzheimer’s disease |
J147 powder is a nootropic developed in 2011, and that can reverse memory loss, slow or reverse Alzheimer’s disease. It belongs to the phenyl hydroxide group and is derived from the curcumin’s curry spice component.
J147 works by reducing the ATP synthesis activity in the mitochondria. Through this, it protects the neuronal cells from age-related brain toxicities. This research came as a breakthrough to researchers since most of the Alzheimer drugs targeted the amyloid plaque deposits in the Alzheimer’s patients’ brains. The Alzheimers drugs did not help much after all.
There have been widespread J147 clinical trials, and it has so far shown to be effective and considered stable. With the promising J147 trial results, it is evident that J147 could assist in the treatment of Parkinson’s and stroke.
- J147 helps in the treatment of neurogenerative diseases.
- It is an experimental drug that has anti-aging properties.
- J147 works by binding to a protein found in the mitochondria (cells that help in the generation of energy).
| Best antiaging nootropic |
Ever thought that your cognitive ability could remain intact even with aging? Magnesium L-Threonate powder is a unique L-threonic acid magnesium salt that replenishes magnesium in one’s brain, making it work more effectively. It is one of the most bioavailable magnesium forms in the market.
The Magnesium L-Threonate powder nootropic works by increasing the synaptic density around the hippocampus region found in the brain. By doing this, it promotes long, short, and working memory in both the young and the aged.
It also increases one’s magnesium status in the body as well as their cognitive abilities.
- The ideal Magnesium L-Threonate dosage is 1500-2000mg
- It helps improve recall, reduced memory due to aging, and also help in the creation of new pathways.
- Magnesium L-Threonate was first created by researchers at MIT who included a Nobel Prize winner.
| Best nootropic in promotion of cardiac function |
Nicotinamide riboside Chloride powder is the newest nicotinamide adenine dinucleotide in the market, which is a vitamin precursor. The advantage with it is that it is easily converted into NAD+ once in the body compared to other NAD+ precursors.
Nicotinamide riboside Chloride bulk powder lowers the risk of suffering from heart disease significantly by reversing age-related changes to your arteries. By raising the NAD+ levels, there is a reduction in the thickness, stiffness that in turn add on the flexibility.
Other Nicotinamide riboside Chloride benefits include aiding in weight loss, lowering cancer risk, assist in the treatment of jet lag, and help in the promotion of healthy muscle aging.
The side effects are insignificant, but the severity could increase with a high dosage.
- It raises blood NAD+ levels by up to 2.7 times.
- The ideal Nicotinamide riboside Chloride dosage is 1000-2000mg per day.
- It is safe with very few Nicotinamide riboside Chloride side effects having been reported.
| Best nootropic for diabetes treatment |
Today, diabetes is one of the leading conditions that people suffer from worldwide. Luckily, this nitrogen-containing compound has proven to help manage the disease. It does this by improving the insulin signaling pathways. Galantamine Hydromide also reduces obesity by lowering inflammation, insulin resistance, body weight, and cholesterol levels.
In the past, it has been used in the treatment of muscular weakness and sensory, and motor dysfunction brought about by central nervous system disorders.
Other Galantamine Hydromide uses include boosting of the cognitive function, reduce arthritic pain, and improve the symptoms in autistic children and Alzheimer’s disease.
- It is obtained from the flowers and bulbs of the Caucasian snowdrop, Daffodil, red spider lily, Garanthus woronowii, and Voronov’s snowdrop.
- Galantamine Hydromide is well absorbed, having an oral bioavailability of 90%.
- It helps in the management of degenerative diseases like Alzheimer’s by enhancing one’s memory, awareness, and ability to perform daily functions.
| Best nootropic in fighting cervical cancer |
The compound 7P powder is a white to off-white powder which was created in a one in series compounds with a purpose to identify dual-acting thromboxane receptor antagonist inhibitors. The nootropics compound 7P powder prompts the growth of gap-43 positive axons leading to the stimulation of axon regeneration in vivo.
The compound 7P has shown the highest activity in fighting cervical tumors by improving the microstructure in a dose-dependent manner.
Some of the 7P powder benefits include; increase in coordination, treatment of alcohol-related brain damage, and prevention of oxidation around the brain. It also helps in improving one’s mood and fighting fatigue.
- It is slightly soluble in water and ethanol.
- The suggested 7P powder dosage should be around 5000mg.
- It takes one to two hours to peak.
| Best glutathione enhancer |
N-Acetyl-L-cysteine ethyl ester (NACET) is the ester form of N-acetylcysteine (NAC) whereby the esterification contributes to the increase in the lipophilicity of NAC hence improving on its pharmacokinetics. This feature further adds to its high absorbency where it gets trapped into the cells leading to its transformation into cysteine and NAC.
It is a GSH precursor with a very high oral bioavailability. NACET works by substituting NAC as a mucolytic agent, as a GSH-related antioxidant, and as a paracetamol antidote.
- Freely soluble in water and organic solvents.
- It gets rapidly absorbed into the cells after administration.
- NACEThelps in the management of degenerative diseases like Alzheimer’s disease.
What to consider before buying nootropics
Choosing the right nootropic requires a bit of research, but it is worth it as it warranties you the results you are looking for. Here are some of the factors to keep in mind while searching for a nootropic;
Taking a nootropic once in a day and forgetting about it is what most people would opt to go for. But in the real sense, finding an excellent nootropic that works with such a dosage interval is hard. Go for those that can be taken twice or thrice a day so that your body gets used to a nicely scheduled dosage throughout the day compared to having one shock dosage.
You don’t want to purchase nootropics that are beyond your budget. You, however, have to consider that all of them are different and their manufacturing methods are unalike hence the price. You also don’t expect to buy high dosages of nootropics with quality ingredients at a peanut price. So before settling on the cheapest one, ensure that check whether it does a good job. That does not, however, mean that you overpay your nootropics; go for what suits your pocket.
Every nootropic has the effect it causes. If you want one that can increase your focus, there is one for that. On the other hand, if you aim to control Alzheimer’s disease, then you ought to find out the best one for that.
Also, some may cause more side effects compared to others. Nobody wants to perform so well at school only to end up having liver failure. After all, your health comes first, and you wouldn’t want to take something that would potentially harm you.
Sometimes, one may want to combine two or more nootropics to get better cognitive effects. You, however, have to note that not all nootropics are safe when stacked. As much as stacks are known to increase potency and to decrease side effects, some may be unsafe for you. You, therefore, have to know the ingredients for each and the way they interact before buying them for stacking.
One more thing that you should look out for is the amount of research done on the nootropic. Some lack the backing of research while some may not be tested on humans. In this era, there are many smart drugs whose research has been satisfactorily done.
So it will only be safe for you to choose a product that has been satisfactorily vetted and confirmed to be effective. Through this, you are assured of some peace of mind as well as avoiding wastage of money by taking things that may harm you or not even work.
Lots have been said about every product by those who have used them in the past. Such information should help you settle on the best and minimize the chance of buying a nootropic that doesn’t work. Go for those that have the best reviews and a few negative ones.
Generally, there is a lot to consider before spending your money on any nootropic. To get the best, you have to factor in all the given points to settle for that which scores most of the points if not all.
Nootropic Smart Drug Powder FAQs
Do nootropics have any side effects?
Yes, they do. The severity of the side effects, however, depends on the nootropic you choose. You could evade the side effects by avoiding low-quality nootropics and high dosages.
What are nootropics used for?
Nootropics are used to enhance human cognitive processes. That includes improvement in the creativity, productivity, anxiety, sleep, and learning through boosting one’s focus, motivation, memory among others.
Are they legal?
The legality of the nootropics differs depending on where you live and the type of nootropic you want to take. In the United States, most of the nootropics are classified as legal dietary supplements whereas, in some of the European countries, nootropics are highly regulated. In some states, they are 100% legal.
Are smart drugs addictive?
Nootropics are not addictive if you are taking them in their pure form. If they are blended with addictive, synthetic ingredients like caffeine, then they may be habit-forming. High-quality nootropics do not pose any risk to chemical addiction and may help you in overcoming an addiction such as smoking cigarettes.
Do nootropics lead to weight loss?
The main aim of taking nootropics is not for weight loss. It is to improve cognition. Though, in some cases, upgrading cognitive performance may lead to weight loss.
Benefits of using nootropics
Every day, we are looking for an edge; something that will make us better than others. Have you thought outside the box and considered the use of nootropics is one of the ways that could ideally give your life a turnaround?
The use of nootropics comes with several benefits, and if you do not notice significant results with the use of one nootropic, you could combine two or more to see more exceptional results.
Below are some of the nootropic benefits;
- Increase your concentration
Have you found yourself thinking about something else that you even forgot the task at hand? It is normal, but sometimes you could feel like you are getting trouble focusing on one thing at a time hence having a bunch of unfinished projects and half-baked ideas. So what do you do?
Taking nootropics have proven to help with that by helping you concentrate more and for a more extended period. Subsequently, you can give every task the attentiveness it deserves even when it feels like you got too much in your mind.
- Enhance memory
Perhaps you have read a particular topic, understood it too well but forgot everything even before the exam day. That should not cause you trouble anymore; taking nootropics have proven to be useful to human memory.
It improves one’s remembrance through the enhancement and repairing of all parts of one’s memory and recalls too. Nootropics also support brain cell development and boost the connectivity of the neurons. Through the improved connection, comprehension, and recall of data information are enhanced.
- Improve your overall brain health
The brain is one of the most significant parts of the body. Its performance, however, gets affected by poor diet and busy schedules. With the use of nootropics, you not only get your memory enhanced, but the overall health of the brain gets improved too.
That is achieved through the increase in the oxygen stream to the brain and maintenance of the neurons and brain cells, which makes the brainwaves more effective.
- Elevate your mood
A foul mood could ruin your day and make you not undertake your activities as they should be. Fortunately, there are available products that could better your mood, making you a happier person. Nootropics can deliver this making you focus and concentrate more on the tasks you may be having.
- Wood S, Sage JR, Anagnostaras SG ( 2014). “Psychostimulants and cognition: Pharmacol. Rev. 66 (1): 193–221.
- Frati P, Kyriakou C, Marinelli E, Vergallo GM, Zaami S, Busardò FP (2015). “Smart drugs for cognitive and physical enhancement:. Curr Neuropharmacol. 13 (1): 5–11.
- Giurgea, Corneliu, (JanuarY, 1977). “Nootropic drugs”. Progress in Neuro-Psychopharmacology. 1 : 235–247