Phenibut powder is a central nervous system depressant that produces both sedating and anti-anxiety effects in users. It is also marketed as a nootropic– a “smart drug” that improves cognitive function and creativity. Amongphenibut users, it is also known as “party powder”, “noofen”, or “pb”. Phenibut is clinically used in Russia to relieve instances of fear, tension,and anxiety, and to improve sleep in neurotic patients. Also, it has been given to patients experiencing post-traumatic stress or disorders characterized by depression.
02 Phenibut powder (1078-21-3) video
03 Phenibut powder (1078-21-3) Base Information
|Chemical name||4-Amino-3-phenylbutyric acid|
|Synonyms||Phenibut; Fenibut; Fenigam; Phenigam; Phenybut; PhGABA|
|Molecular Weight||179.219 g/mol|
|Melting Point||252.5°C (rough estimate)|
|Half Life||5.3 hours|
|Solubility||DMSO (Slightly), Methanol (Slightly)|
|Storage Condition||Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).|
|Application||Phenibut is a derivative of γ-Aminobutyric Acid (A602920); an important inhibitory neurotransmitter. Phenibut possesses neuroprotective activity.|
04 Phenibut (1078-21-3) Description
Phenibut powder can probably best be described as a supplement, although it doesn’t necessarily have a rigid classification in the U.S. It is an uncontrolled substance, which means it’s available without a prescription, and it’s not illegal to possess it, sell it or use it, at least not in the United States.
Phenibut’s powder use stems back to the 1960s, where it was used in Russia as an anti-anxiety medicine.
Phenibut acts as a central nervous system depressant, and it has both relaxing and euphoric effects for users. It’s similar in structure to a neurotransmitter called GABA, which has a calming effect on the neuron activity in the brain. Unlike the supplement GABA, phenibut does have the ability to cross the blood-brain barrier, so it has psychoactive effects. Specific things phenibut is often used to treat include anxiety, depression, PTSD, insomnia, and alcoholism. It’s also sometimes used by people who are going through withdrawal from drugs or alcohol.
Phenibut has sedative effects, and it’s also been shown to increase dopamine levels in the brain, which is why some people may find that it has euphoric effects.
05 Phenibut powder (1078-21-3) History
Phenibut powder is a derivative of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter produced endogenously in the human brain. As an inhibitory chemical, GABA blocks nerve impulses, helping induce calmness and relieves feelings of anxiety.
Unlike the traditional supplement GABA, which researchers believe is unable to sufficiently cross the blood-brain barrier, the chemical structure of phenibut may allow it to more easily cross over this protective barrier and into the brain.
Phenibut is thought to exhibit much of its effects on human mood and cognition through its interactions with GABA receptors. It also has an effect on benzodiazepine and dopamine receptors.
06 Phenibut (1078-21-3) Application
Phenibut is a chemical similar to a brain chemical called gamma-aminobutyric acid (GABA). It is used as a recreational drug and as a medicine.Phenibut is used for anxiety, fear, trouble sleeping (insomnia), tension, stress, fatigue, post-traumatic stress disorder (PTSD), depression, alcoholism, and irregular heartbeat. It is also used for improving memory, learning, and thinking.
07 Phenibut (1078-21-3) More research
Phenibut, sold under the brand names Anvifen, Fenibut, and Noofen among others, is a central nervous system depressant with anxiolytic and stimulant effects which is used in the treatment of anxiety, insomnia, and for a variety of other indications. It is usually taken by mouth as a tablet, but can also be given as an intravenous infusion. Many people have taken to this compound and have found fantastic results. However, before trying this compound it is essential to know the ideal phenibut dosage for any particular application. Because of this drug’s dosage sensitivity, it is easy to negate the beneficial effects of phenibut by incorrect doses.
08 Phenibut (1078-21-3) Document Download
09 Phenibut (1078-21-3) Reference
- Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev 2001;7:471–81 [PMC free article] [PubMed] [Google Scholar]
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- Schmidt MM, Sharma A, Schiifano F, et al. “Legal highs” on the net—evaluation of UK-based websites, products and product information. Forensic Sci Int 2011;206:92–7 [PubMed] [Google Scholar]
- Watson R. EU drug monitoring agency voices concerns over “legal highs”. BMJ 2010;341:c6491. [PubMed] [Google Scholar]
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- 01. Overview
- 02. Phenibut powder (1078-21-3) video
- 03. Phenibut powder (1078-21-3) Base Information
- 04. Phenibut (1078-21-3) Description
- 05. Phenibut powder (1078-21-3) History
- 06. Phenibut (1078-21-3) Application
- 07. Phenibut (1078-21-3) More research
- 08. Phenibut (1078-21-3) Document Download
- 09. Phenibut (1078-21-3) Reference