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Dihydrocaffeic acid (DHCA) powder 1078-61-1
Dihydrocaffeic acid (DHCA) powder Chemical Base Information
| Name | Dihydrocaffeic acid |
| CAS | 1078-61-1 |
| Purity | 98% |
| Chemical name | 3,4-dihydroxy-benzenepropanoic acid |
| Synonyms | 3,4-dihydroxy-benzenepropanoic acid
2,3-Dihydrocaffeic acid 3-(3,4-dihydroxyphenyl)propanoic acid 3-(3,4-dihydroxyphenyl)propionic acid 3-(3′,4′-Dihydroxyphenyl)propionic acid 3,4-dihydroxy-dihydrocinnamic acid 3,4-dihydroxybenzenepropanoic acid hydrocaffeic acid |
| Molecular Formula | C9H10O4 |
| Molecular Weight | 182.2 |
| Boling Point | / |
| InChI Key | DZAUWHJDUNRCTF-UHFFFAOYSA-N |
| Form | powder |
| Appearance | powder |
| Half Life | / |
| Solubility | DMF: 25mg/mL
DMSO: 25mg/mL Ethanol: 10mg/mL PBS (pH 7.2): 2.5mg/mL |
| Storage Condition | RT |
| Application | Antioxidant, dietary supplements, health supplements |
| Testing Document | Available |
What Is Dihydrocaffeic acid (DHCA) Powder?
Powder Dihydrocaffeic acid (DHCA) also known as 3,4-Dihydroxyhydrocinnamic acid, is a metabolite product of the hydrogenation of caffeoylquinic acids, occurring in normal human biofluids, with potent antioxidant properties. Dihydrocaffeic acid (DHCA) has been detected in human plasma following coffee ingestion and is increased with some dietary sources, such as after ingestion of phenolic constituents of artichoke leaf extract . Polyphenol-rich foods such as vegetables and fruits have been shown to significantly improve platelet function in ex vivo studies in humans . Its antioxidant activity has been tested to reduce ferric iron in the ferric reducing antioxidant power (FRAP) assay, and it has been suggested that its catechol structure conveys the antioxidant effect in plasma and in erythrocytes . 3,4-Dihydroxyhydrocinnamic acid is a microbial metabolite found in Bifidobacterium, Escherichia, Lactobacillus, and Clostridium.
Dihydrocaffeic acid (DHCA) powder Application
Antioxidant, dietary supplements, health supplements.
What Are The Benefits Of Dihydrocaffeic acid (DHCA) powder?
The most important benefits of Dihydrocaffeic acid (DHCA) is antioxidant.
Chronic UVB exposure promotes oxidative stress, directly causes molecular damage, and induces aging-related signal transduction, leading to skin photoaging. Dihydrocaffeic acid (DHCA) is a phenolic compound with potential antioxidant capacity and is thus a promising compound for the prevention of UVB-induced skin photodamage.
Dihydrocaffeic acid (DHCA) Vs Caffeic acid (CA)
Caffeic acid (CA) has been implied as an important source of natural antioxidants in various agricultural products. We compared the antioxidative activity of CA and dihydrocaffeic acid (DHCA) in lard and the low-density lipoprotein (LDL) system to know the role of the 2,3-double bond on the appearance of its antioxidative property. DHCA was more effective than CA in enhancing oxidative stability of lard at 60 °C. Inhibition by DHCA of copper ion-induced oxidation of human LDL was less effective than that by CA, whereas there was no significant difference between the two compounds in the capacity of 1,1-diphenyl-2-picrylhydrazyl radical scavenging and the activity of lipid peroxyl radical scavenging in solution. It can be concluded that the 2,3-double bond in the structure of CA affects the efficiency of antioxidative activity depending on the environment where the oxidation happens, although it is rarely responsible for its inherent activity.
Buy Dihydrocaffeic acid (DHCA) In Bulk
Powder Dihydrocaffeic acid (DHCA) is a metabolite of caffeic acid and exhibits antioxidant activity. It has a role as an antioxidant and a human xenobiotic metabolite. It derives from a 3-phenylpropionic acid. It is a conjugate acid of a 3-(3,4-dihydroxyphenyl)propanoate.
Wisepowder supply pure Dihydrocaffeic acid (DHCA) powder in bulk, which is the main ingredient use to make dietary supplement for body health.
Dihydrocaffeic acid (DHCA) powder Reference
- Perrone D, Farah A, Donangelo CM (2012) Influence of coffee roasting on the incorporation of phenolic compounds into melanoidins and their relationship with antioxidant activity of the brew.
- Journal of agricultural and food chemistry 60, 4265-4275 [PubMed:22490054]
- Huang J, de Paulis T, May JM (2004)Antioxidant effects of dihydrocaffeic acid in human EA.hy926 endothelial cells.The Journal of nutritional biochemistry 15, 722-729 [PubMed:15607645]Wang, Jun; Hodes, Georgia E.; Zhang, Hongxing; Zhang, Song; Zhao, Wei; Golden, Sam A.; Bi, Weina; Menard, Caroline; Kana, Veronika; Leboeuf, Marylene; Xie, Marc (2018-02-02). “Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice”. Nature Communications. 9 (1): 477. doi:10.1038/s41467-017-02794-5. ISSN 2041-1723. PMC 5797143. PMID 29396460. CC-BY icon.svg Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License
- PubChem. “3-(3,4-Dihydroxyphenyl)propionic acid”. pubchem.ncbi.nlm.nih.gov. Retrieved 2019-12-13.
