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Nooglutyl powder (112193-35-8)

Nooglutyl powder is a nootropic agent being studied at the Research Institut of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia. In animal models, it has a variety of central nervous system effects. It could be used in medicine, health products, food, beverage, cosmetics, biological and chemical reagents and other industries.

Manufacture:  Batch Production
Package:  1KG/bag, 25KG/drum
Wisepowder has the capability to produce and supply large quantity. All production under cGMP condition and strict quality control system, all testing documents and sample available.

Nooglutyl powder (112193-35-8) video

 

 

Nooglutyl powder (112193-35-8) Base Information

Name Nooglutyl powder
CAS 112193-35-8
Purity 98%
Chemical name N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid

N-(5-hydroxynicotinoyl)-L-glutamic acid

N-(5-Hydroxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide;nooglutil

Synonyms nooglutil;N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid;N-[(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamicacid;ONK-10;L-GlutaMic acid, N-[(5-hydroxy-3-pyridinyl)carbonyl]-;Nooglutyl
Molecular Formula C11H12N2O6
Molecular Weight 268.22 g/mol
Melting Point N/A
InChI Key XFZGYOJFPGPYCS-QMMMGPOBSA-N
Form solid
Appearance White fine powder
Half Life 30 minutes to 3 hours
Solubility slightly soluble in water and in ethanol.
Storage Condition Stored in a cool and dry area, kept away from moisture and strong light or high temperature.
Application Used in medicine, health products, food, beverage,cosmetics, biological and chemical reagents and   other industries.
Testing Document Available

 

Nooglutyl powder (112193-35-8) General Description

Nooglutyl is a nootropic agent being studied at the Research Institute of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia. In animal models, it has a variety of central nervous system effects.

Experiments on rats demonstrate that nooglutyl exhibits pronounced vestibular-protective properties and by its antimotion activity does not rank below classic vestibular protectors, such as scopolamine and diprazine. Electrophysiological experiments on cats show that nooglutyl alters spontaneous activity in 80% of cortical neurons (somatosensory zone I and area 5 of the parietal association cortex) and considerably weakens effects caused by motion sickness: activation of single unit activity of somatosensory zone I and inhibition of neuron responses to somatic stimulation. This property of the preparation is believed to form the basis of its antimotion effect.

 

Nooglutyl powder (112193-35-8) History

Nooglutyl is a nootropic agent that was studied at the Research Institute of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia.In animal models, it has a variety of central nervous system effects.

 

Nooglutyl powder (112193-35-8) Mechanism Of Action

Experiments on rats demonstrate that nooglutyl exhibits pronounced vestibular-protective properties and by its antimotion activity does not rank below classic vestibular protectors, such as scopolamine and diprazine. Electrophysiological experiments on cats show that nooglutyl alters spontaneous activity in 80% of cortical neurons (somatosensory zone I and area 5 of the parietal association cortex) and considerably weakens effects caused by motion sickness: activation of single unit activity of somatosensory zone I and inhibition of neuron responses to somatic stimulation. This property of the preparation is believed to form the basis of its antimotion effect.

 

Nooglutyl powder (112193-35-8) Application

Nooglutyl is a nootropic agent being studied at the Research Institute of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia.In animal models, it has a variety of central nervous system effects.

 

Nooglutyl powder (112193-35-8) Reference

  • Flekhter, Oxana B. (2000). “Nooglutil, Russian Academy of Medical Science”. Current Opinion in Central & Peripheral Nervous System Investigational Drugs. 2 (4): 491–
  • V. Yasnetsov; V. A. Pravdivtsev; V. M. Popov; T. A. Voronina; N. M. Kiseleva; S. B. Kozlov (May 1995). “Antimotion Effect of Nooglutyl and Its Neuronal Mechanism”. Bulletin of Experimental Biology and Medicine. 119 (5): 515–516. doi:10.1007/BF02543440. PMID 7579248. Retrieved 2011-02-08.
  • Voronina, TA; Borlikova, GG; Garibova, TL; Proskuryakova, TV; Petrichenko, OB; Burd, SG; Avakyan, GN (2002). “Effect of nooglutil on benzodiazepine withdrawal syndrome and binding of 3H-spiperone with D2 receptors in rat striatum”. Bulletin of experimental biology and medicine. 134 (5): 448–

 

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