Lorcaserin HCL powder (1431697-94-7)
Lorcaserin HCL powder is the hydrochloride form of lorcaserin. Lorcaserin brand name is “belviq”, it is an orally administered medication that promotes weight loss. It is used with diet and exercise in overweight adults with a weight-related medical problem or obese adults to lose weight and keep it off.
Manufacture: Batch Production
Package: 1KG/bag, 25KG/drum
Lorcaserin HCL powder (1431697-94-7) video
Lorcaserin HCL (1431697-94-7) Base Information
|Chemical name||8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride|
|Molecular Weight||232.15 g/mol|
|Appearance||White to Off-white powder|
|Solubility||Water solubility is greater than 400 mg/mL|
|Storage Condition||Store at room temperature, in a sealed airtight container, keep the air out, protected from heat, light and humidity.|
|Application||Lorcaserin is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight.|
Lorcaserin HCL powder General Description
Lorcaserin HCL powder affects chemical signals in the brain that control appetite. Lorcaserin HCL powder is used together with diet and exercise to treat obesity.
Lorcaserin is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.
Lorcaserin HCL powder (1431697-94-7) History
Lorcaserin HCL is a weight-loss drug developed by Arena Pharmaceuticals.
Lorcaserin HCL powder Mechanism Of Action
Lorcaserin HCL powder works by helping you feel full with smaller meals.
Lorcaserin is a selective 5-HT2C receptor agonist,and in vitro testing of the drug showed reasonable selectivity for 5-HT2C over other related targets.5-HT2C receptors are located almost exclusively in the brain, and can be found in the choroid plexus, cortex, hippocampus, cerebellum, amygdala, thalamus, and hypothalamus. The activation of 5-HT2C receptors in the hypothalamus is supposed to activate proopiomelanocortin (POMC) production and consequently promote weight loss through satiety.This hypothesis is supported by clinical trials and other studies. While it is generally thought that 5-HT2C receptors help to regulate appetite as well as mood, and endocrine secretion,the exact mechanism of appetite regulation is not yet known. Lorcaserin has shown 100x selectivity for 5-HT2C versus the closely related 5-HT2B receptor, and 17x selectivity over the 5-HT2A receptor.
Lorcaserin HCL powder (1431697-94-7) Application
Lorcaserin HCL powder is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Lorcaserin HCL powder belongs to a class of drugs known as serotonin receptor agonists. It is thought to work by affecting a certain part of the brain that helps control your appetite.
Lorcaserin HCL powder More research
Lorcaserin will not treat any underlying health condition (such as heart disease, diabetes, high blood pressure).
Lorcaserin HCL powder (1431697-94-7) Reference
- New Diet Drug Lorcaserin Wins Vote From FDA Panel”. webmd. 10 May 2012. Archived from the original on 12 May 2012.
- ”FDA Issues Complete Response Letter for Lorcaserin New Drug Application”. 23 October 2010. Archived from the original on 24 October 2010.
- ”BELVIQ and BELVIQ XR HCP Home Page”. www.belviqhcp.com. Archived from the original on 2016-06-16.
-  Bray, GA; Frühbeck, G; Ryan, DH; Wilding, JP (7 May 2016). “Management of obesity”. Lancet. 387 (10031): 1947–56. doi:10.1016/S0140-6736(16)00271-3. PMID 26868660.
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