Although COENZYME Q10(CoQ10) powder plays a key role in the body, most healthy people have enough CoQ10 naturally. There is some evidence that adding more — in the form of CoQ10 supplements — may be beneficial. Increasing age and some medical conditions are associated with dropping levels of CoQ10. But in these cases, it’s uncertain that adding CoQ10 will have an effect.

COENZYME Q10(CoQ10) powder has been used to treat many different conditions. There’s evidence that CoQ10 supplements can lower blood pressure slightly. CoQ10 is also used to treat heart failure and other heart conditions, possibly helping to improve some symptoms and lessen future cardiac risks when combined with regular medications, but the evidence is conflicting.

Though still controversial, some preliminary evidence suggests that CoQ10 may help to prevent or treat the adverse effects, such as muscle pains and liver problems, of taking statin-type cholesterol drugs.

Preliminary studies have shown that CoQ10 may slow, but not stop, the progression of Alzheimer’s disease. Additional research is needed to confirm this effect.

CoQ10 has also been studied as a preventive treatment for migraine headaches, though it may take several months to work. It was also been studied for low sperm count, cancer, HIV, muscular dystrophy, Parkinson’s disease, gum disease, and many other conditions. However, the research has not found any conclusive benefits. Although CoQ10 is sometimes sold as an energy supplement, there is no evidence that it will boost energy in a typical person.

Supplementing with CoQ10 appears to be well tolerated by humans and have low toxicity.In fact, participants in some studies showed no major side effects taking daily coenzyme q10 dosage of 1,200 mg for 16 months.

However, if coenzyme q10 side effects appear, it is recommended to divide the daily coenzyme q10 dosage into two to three smaller doses.

[1] Folkers K, Hanioka T, Xia LJ, McRee JT, Langsjoen P (April 1991). “Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex”. Biochemical and Biophysical Research Communications. 176 (2): 786–91. doi:10.1016/S0006-291X(05)80254-2. PMID 1673841.

[2] Nakamura R, Littarru GP, Folkers K, Wilkinson EG (April 1974). “Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10”. Proceedings of the National Academy of Sciences of the United States of America. 71 (4): 1456–60. Bibcode:1974PNAS…71.1456N. doi:10.1073/pnas.71.4.1456. PMC 388248. PMID 4151519.

[3] “Mitochondrial disorders in children: Co-enzyme Q10”. UK: National Institute for Health and Care Excellence. 28 March 2017.

[4] Weber C, Bysted A, Hłlmer G (1997). “The coenzyme Q10 content of the average Danish diet”. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition. 67 (2): 123–9. PMID 9129255.