Coenzyme Q10 (CoQ10) powder (303-98-0)

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Name:Coenzyme Q10 (CoQ10)

CAS:303-98-0

Molecular Formula:C59H90O4

STORAGE:Store in a cool and dry place. Keep away from direct sunlight and heat.

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COENZYME Q10 (CoQ10) powder (303-98-0) video

 

 

COENZYME Q10 (CoQ10) (303-98-0) Base Information

Name Coenzyme Q10
CAS 303-98-0
Purity 40% (water solubility), 98%
Chemical name Coenzyme Q10
Synonyms ubidecarenone

ubiquinone-10

CoQ10

Molecular Formula C59H90O4
Molecular Weight 863.3 g/mol
Melting Point 50-52ºC
InChI Key ACTIUHUUMQJHFO-UPTCCGCDSA-N
Form Solid
Appearance
Half Life The pharmacokinetic properties may vary between different brands but studies have reported a half life of ubidecarenone of 21.7 h.
Solubility water solubility: Sparingly soluble
Storage Condition Store in a sealed airtight container, keep the air out, protected from heat, light and humidity.
Application CoQ10 acts as an antioxidant, which protects cells from damage and plays an important part in the metabolism.
Testing Document Available

 

COENZYME Q10 (CoQ10) General Description

Coenzyme Q10 (CoQ10) powder is a nutrient that occurs naturally in the body. CoQ10 is also in many foods we eat. Coenzyme Q10 (CoQ10) powder acts as an antioxidant, which protects cells from damage and plays an important part in the metabolism.

 

COENZYME Q10 (CoQ10) (303-98-0) History

COENZYME Q10(CoQ10) powder is a coenzyme family that is ubiquitous in animals and most bacteria (hence the name ubiquinone). In humans, the most common form is Coenzyme Q10 or ubiquinone-10. CoQ10 is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition;however, it is sold as a dietary supplement.

It is a 1,4-benzoquinone, where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail. In natural ubiquinones, the number can be anywhere from 6 to 10. This family of fat-soluble substances, which resemble vitamins, is present in all respiring eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way.Organs with the highest energy requirements—such as the heart, liver, and kidney—have the highest CoQ10 concentrations.

 

COENZYME Q10 (CoQ10) (303-98-0) Application

COENZYME Q10(CoQ10) powder is a compound made by your body and stored in the mitochondria of your cells,it is a nutrient that occurs naturally in the body. CoQ10 is also in many coenzyme q10 foods foods we eat.The important 9 benefits of COENZYME Q10(CoQ10) powder may include:

  • It May Help Treat Heart Failure
  • It Could Help With Fertility
  • It Might Help Keep Your Skin Young
  • It Could Reduce Headaches
  • It Could Help With Exercise Performance
  • It Could Help With Diabetes
  • It Might Play a Role in Cancer Prevention
  • It Is Good for the Brain
  • CoQ10 Could Protect the Lungs

 

COENZYME Q10 (CoQ10) More research

Although COENZYME Q10(CoQ10) powder plays a key role in the body, most healthy people have enough CoQ10 naturally. There is some evidence that adding more — in the form of CoQ10 supplements — may be beneficial. Increasing age and some medical conditions are associated with dropping levels of CoQ10. But in these cases, it’s uncertain that adding CoQ10 will have an effect.

COENZYME Q10(CoQ10) powder has been used to treat many different conditions. There’s evidence that CoQ10 supplements can lower blood pressure slightly. CoQ10 is also used to treat heart failure and other heart conditions, possibly helping to improve some symptoms and lessen future cardiac risks when combined with regular medications, but the evidence is conflicting.

Though still controversial, some preliminary evidence suggests that CoQ10 may help to prevent or treat the adverse effects, such as muscle pains and liver problems, of taking statin-type cholesterol drugs.

Preliminary studies have shown that CoQ10 may slow, but not stop, the progression of Alzheimer’s disease. Additional research is needed to confirm this effect.

CoQ10 has also been studied as a preventive treatment for migraine headaches, though it may take several months to work. It was also been studied for low sperm count, cancer, HIV, muscular dystrophy, Parkinson’s disease, gum disease, and many other conditions. However, the research has not found any conclusive benefits. Although CoQ10 is sometimes sold as an energy supplement, there is no evidence that it will boost energy in a typical person.

Supplementing with CoQ10 appears to be well tolerated by humans and have low toxicity.In fact, participants in some studies showed no major side effects taking daily coenzyme q10 dosage of 1,200 mg for 16 months.

However, if coenzyme q10 side effects appear, it is recommended to divide the daily coenzyme q10 dosage into two to three smaller doses.

 

COENZYME Q10 (CoQ10) powder (303-98-0) Reference

[1] Folkers K, Hanioka T, Xia LJ, McRee JT, Langsjoen P (April 1991). “Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex”. Biochemical and Biophysical Research Communications. 176 (2): 786–91. doi:10.1016/S0006-291X(05)80254-2. PMID 1673841.

[2] Nakamura R, Littarru GP, Folkers K, Wilkinson EG (April 1974). “Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10”. Proceedings of the National Academy of Sciences of the United States of America. 71 (4): 1456–60. Bibcode:1974PNAS…71.1456N. doi:10.1073/pnas.71.4.1456. PMC 388248. PMID 4151519.

[3] “Mitochondrial disorders in children: Co-enzyme Q10”. UK: National Institute for Health and Care Excellence. 28 March 2017.

[4] Weber C, Bysted A, Hłlmer G (1997). “The coenzyme Q10 content of the average Danish diet”. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition. 67 (2): 123–9. PMID 9129255.

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