Amino Tadalafil powder (385769-84-6)

Amino tadalafil powder is a potent inhibitor of phosphodiesterase 5 (PDE5). PDE5, an enzyme found primarily in the smooth muscle of the corpus cavernosum, selectively cleaves and degrades cGMP to 5′-GMP. PDE5 inhibitors are similar in structure to cGMP and they competitively bind to PDE5 and inhibit cGMP hydrolysis, thus enhancing the effects of NO, resulting in prolonging an erection.

Amino tadalafil vs tadalafil, Amino tadalafil is a drug analog of tadalafil.

Inhibitor of phosphodiesterase 5 (PDE5). PDE5, an enzyme found primarily in the smooth muscle of the corpus cavernosum, selectively cleaves and degrades cGMP to 5′-GMP. PDE5 inhibitors are similar in structure to cGMP and they competitively bind to PDE5 and inhibit cGMP hydrolysis, thus enhancing the effects of NO, resulting in prolonging an erection.

Amino tadalafil is an analog of tadalafil, a potent inhibitor of phosphodiesterase 5 with applications in several conditions, including used in the treatmen of erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.

In rats treated with both melatonin and tadalafil, the recoveries were more pronounced than in rats given either melatonin or tadalafil alone. The ICP/mean arterial pressure value in vehicle-treated rats was significantly higher than in the control group, while in the tadalafil- and tadalafil + melatonin-treated groups have returned this value had returned to control levels. In addition, as an individual treatment, and especially when combined with tadalafil, melatonin prevented spinal cord injury (SCI)-induced oxidative damage to cavernosal tissues and restored ED, most likely due to its anti-oxidant effects

COA

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