YK11 powder, known as YK-11, or (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester as its chemical name, is the newest ingredient in the SARMs family in recent years. YK11 is said to be the most potent SARM without serious side effects such as hair loss, aggression, prostate enlargement, etc. DHT is something people talk with when come across YK11. We may compare them in details in the following.
YK11 also known as Myostine, is considered one of the strongest SARMs on the market. In fact, it’s so strong and has comparable anabolic activity to steroids that it may actually be a synthetic steroid that was mislabeled a SARM in the first place.
YK11 was first studied by Japanese researcher Yuichiro Kanno in 2011. It was found to be a partial agonist of the Androgen Receptor (AR) with gene-selective properties, leading researchers to suggest that the compound is a SARM.
To date, limited studies have been undertaken, although preliminary findings in vitro on muscle cells are very promising. Initial studies suggest that YK11 may have greater muscle building effects than those of DHT and a propensity to act as a myostatin inhibitor.
YK11 powder (431579-34-9) History
Yk11 was initially studied by a Japanese researcher named Yuichiriro Kanno in the year 2011. According to Yuichirio, the drug was a selective androgen receptor modulator, but currently, researchers think otherwise. Since then, the limited studies that have been carried out have claimed that YK11 acts as a myostatin inhibitor. Its molecule structure was also found to be very different and quite unique. However, since YK11 is still new in the market, there still does not exist any established naming for the drug.
YK11 powder (431579-34-9) Mechanism Of Action
YK11 as a myostatin inhibitor
Myostatin is a protein that, when it is within the body, myostatin restricts the muscle tissue growth and production. In this way, myostatin is bad to bodybuilders. By inhibiting myostatin, YK11 induces muscle cells to make more follistatin, and bodybuilders can experience significantly more muscle mass and exponential strength increases. In this sense, YK11 can be as good as testosterone in terms of muscle strengthening.
YK11 as an androgen
In addition, YK-11 is an androgen. YK11 attaches itself to the AR (androgen receptor), and has been discovered that muscle cells produce more anabolic factors if exposed to 500 nmol (nanomoles) YK11 than if you expose the same muscle cells to 500 nmol DHT. YK11 fortifies parts of your muscles in the same manner as testosterone and the only difference isthat it doesn’t have the additional side-effect. The primary factor to keep in mind about YK11 is it may also provide you with a strengthening boost when you’re during a workout session so apply for longer without encountering any fatigue. On the top of that, it may also help you to modify your body genetics so that you can build more muscle and faster than before.
YK11 powder (431579-34-9) Application
YK11 induces muscle cells to make more follistatin (more than DHT does) – a strong myostatin inhibitor. YK11 works through the androgen receptor.
With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it’s as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
SRM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique! Check out the newest and most popular YK-11 based product by Focused Nutrition. It is absolutely KILLING IT in the SARM world.
YK11 powder (431579-34-9) More research
There is no recommended dose for YK11. Some say that it can be taken at doses between 5 and 8 mg per day at an eight-week cycle, some sports nutrition companies say that the YK11 Muscle Building Cycle should have an administered protocol of 4mg 3 times daily to provide the greatest body composition effects, strength and lean mass. I believe both recommendation for YK11 are right, depending on your own situation.
YK11 powder (431579-34-9) Reference
1.Kanno Y, Ota R, Someya K, Kusakabe T, Kato K, Inouye Y. Selective androgenreceptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 2013;36(9):1460-5.