PRL-8-53 powder (51352-87-5)

PRL-8-53 powder is a Nootropic chemical that is currently under research. The product is made with Benzoic acid and phenyl methylamine. Right now, PRL-8-53 has largely been studied as a hypermnesic drug in humans. In other words, it can be used as a remedy to improve cognitive functions and memory. The drug was first synthesized in the 1970s by a professor of chemistry at Creighton University. Even though PRL-8-53 is not classified as a medical treatment for disease or any illnesses, it has been known to have potent Nootropic effects. That’s why PRL-8-53 and Adderall are two terms used together. There was even one clinical trial conducted in 1978 that showed study participants had an overall improvement in recollection when treated with 5 milligrams of PRL-8-53. There were also no PRL-8-53 side effects reported during the trial. The PRL-8-53 sold these days is however a synthetic supplement. This means that it is manufactured in a lab, packaged and distributed to customers. Even though only one human study has been conducted on the effects of PRL-8-53 over the last 40 years, there is a lot of belief that the drug is probably one of the most powerful Nootropics in the market.

Manufacture:  Batch Production
Package:  1KG/bag, 25KG/drum
Wisepowder has the capability to produce and supply large quantity. All production under cGMP condition and strict quality control system, all testing documents and sample available.

PRL-8-53 powder (51352-87-5) video


PRL-8-53 powder (51352-87-5) Base Information

Name PRL-8-53 powder
CAS 51352-87-5
Purity 98%
Chemical name Prl-8-53


methyl 3-[2-[benzyl(methyl)amino]ethyl]benzoate

methyl 3-{2-[benzyl(methyl)amino]ethyl}benzoate


Synonyms 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride

3-(2-(Methyl(phenylmethyl)amino)ethyl)benzoic acid methyl ester hydrochloride

Molecular Formula C18H21NO2
Molecular Weight 283.371 g/mol
Melting Point 149-152℃.
Form Solid
Appearance white powder
Half Life 2-4 hours
Solubility Soluble to 25 mM in Ethanol, Soluble to 50 mM in Water.
Storage Condition Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Application PRL-8-53 is a nootropic research chemical derived from benzoic acid and phenylmethylamine with memory-enhancing effects, used in neuroscience research related to memory enhancement and protection against memory impairment.
Testing Document Available


What is PRL-8-53 powder?

PRL-8-53 psychonaut is a Nootropic chemical that was discovered in the 1970s. It is completely non-toxic. In the only human trial conducted over the last four decades, no PRL-8-53 side effects were reported. The drug also showed no harmful effects when used on rats. PRL-8-53 may also be referred to as Methyl 3.

So far, the chemical is marketed as a memory enhancement drug that may offer additional cognitive benefits. The evidence to support this is there but we have seen very few trials so far on the potential benefits of PRL-8-53. Although based on PRL 8 53 Reddit 2019 reviews a lot of people are already using the drug to enhance memory, research is still needed to explore any other potential benefits PRL-8-53 could offer.


How Does PRL-8-53 powder Work?

PRL-8-53 modafinil has been in existence for the best part of 50 years now. But believe or not, its mechanisms of action are still a huge mystery. There is however some research out there trying to explain how PRL-8-53 works, especially as a Nootropic supplement. Some researchers argue that the drug may enhance the action of acetylcholine, a powerful neurotransmitter that is significantly crucial in learning and memory.

However, how the drug affects acetylcholine is still unknown. We are not sure to what extent PRL-8-53 triggers the action of acetylcholine either. There is also some research suggesting that PRL-8-53 may trigger increased production of dopamine. Enhanced production of dopamine is known to enhance memory. It may also have positive effects on enhancing mood, reducing fatigue, and dealing with anxiety.

Some researchers have also suggested that PRL-8-53 can trigger the production of serotonin, the happy hormone in the brain in charge of regulating mood and depression. However, these are all theoretical suggestions. In the single human study done on the effects of PRL-8-53, researchers did not track changes in neurotransmitter levels.

Even though during the human study PRL-8-53 showed a lot of promise in improving memory, there was no way to directly link these results to increased neurotransmitter action. Nonetheless, as we continue to get more research on the action of the drug, we may get a better understanding of the PRL-8-53 half life, how the drug works and its possible effects.


PRL-8-53 Benefits and Effects

Despite the limited clinical evidence on the possible effects of PRL-8-53, there are certain PRL-8-53 benefits that you can expect in case you decided to use it. Here is a simple breakdown of each of them.

Memory Enhancement

As we have already noted above, PRL-8-53 is marketed as a Nootropic drug. This simply means that it has shown promise in enhancing memory and learning among users. In the only human study conducted on the effects of this drug, PRL-8-53 showed a lot of promise as a memory-enhancing product. The double-blinded study used memorization to measure memory. Participants were treated with a dose of PRL-8-53 and were then asked to recall words they had read earlier after 24 hours.

It emerged that people who were treated with PRL-8-53 had better recollection compared to the placebo group. The study was conducted on participants above 30 years old. However, we have not seen any other clinical trials replicating these results. But based on the PRL-8-53 examine and reviews of users who are already using the product, it is clear that it works quite effectively as a memory enhancing supplement. There is also some research suggesting that PRL-8-53 may help to enhance verb fluency among users. We have not seen any proof of this thus far but some people are corroborating it with their reviews.

Drug Interactions

Even with its memory improving capabilities, Prl-8-53 Nootropics may also have some side effects if combined with other drugs. Since there is very little research on how PRL-8-53 works and its effects, we cannot definitely establish the kind of interactions it may have with other drugs. But there is one thing you can do. If you are taking other drugs or you are under any form of medication, consult with your physician before using PRL-8-53. Pregnant women should also not use the drug.


How to Use PRL-8-53

PRL-8-53 sublingual is ingested orally using the mouth. The drug is then absorbed into the blood through the gastrointestinal system. There is very little information about the possible dosage for PRL-8-53. However, from the only human trial done on the drug, patients were treated with a 5 milligrams PRL-8-53 dosage. In that case, we can argue that this would be the ideal dosage for people using PRL-8-53. There is some good news though.

During the clinical trials, no side effects were actually reported. The drug is therefore considered non-toxic at this dosage. Other studies done on rats also showed PRL-8-53 is a safe drug to use. However, there is still a risk of serious side effects if the drug is abused.


PRL-8-53 Nootropics Stack

Since PRL-8-53 capsules are experimental drugs, there is very little information about how they interact with other drugs. We also don’t have any information about stacking PRL-8-53. Because of this, it would be best to use the drug on its own. PRL-8-53 is already a very potent Nootropic so you don’t need to combine it with any other supplements to make it work. But as we learn more about the drug in future research, we may get a clear understanding on the best way to stack it.


PRL-8-53 Side Effects and Safety

The challenge with many experimental drugs is that you don’t really get to know what they can do. We all know that PRL-8-53 is such a potent Nootropic based on the one clinical trial done and the reviews of users. But there is very little research on its possible side effects. The only good news is that, in the only clinical study done involving humans, PRL-8-53 was determined to be a safe and non-toxic substance to use. However, there are certain conditions that may make the use of PRL-8-53 dangerous.

First, pregnant women are not allowed to use PRL-8-53, or any other type of Nootropic. Secondly, it may be nice to consult with your doctor first before using PRL-8-53. There is very little research on PRL-8-53 drug interactions. There is no way of knowing how the supplement may interact with any other medications that you are using. To be on the safe side, just talk to your doctor and see if PRL-8-53 is safe for you.

Do not overdose on PRL-8-53 too. About 5 milligrams of PRL-8-53 should be enough to get you the results you need. Using too much at any given time may cause unwanted side effects. Finally, make sure you are using a genuine PRL-8-53 powder. There are several vendors in the market today that claim to offer these supplements. Take care and choose sellers that can guarantee a pure and high-quality PRL-8-53 supplement


PRL-8-53 Powder Buy

PRL-8-53 powder is available through nootropics powder online vendors. The supplement is sold as a powder and can be purchased and shipped to you in selected countries around the world including the United States. However, even with the amazing variety of vendors out there, you still need to be very careful to ensure you get a genuine product. PRL-8-53 can only work for you if you buy a quality and pure supplement. Buying from trusted PRL-8-53 powder suppliers who have done this for years is always a great idea.

Here are some tips that may help you:

  • Check out what other customers are saying about a vendor before buying from them. Vendors with excellent customer reviews over a long period of time are more likely to offer a quality product.
  • Do not focus too much on the cost. The main reason why most people end up with a low-quality supplement is because they insist on saving too much. It’s better to pay a little extra for a product that will work.
  • Check out the years a vendor has been selling. We have nothing against new vendors but you are more likely to get a quality product from companies that have been doing this for years.

PRL-8-53 is a potent supplement that can help with memory and learning. Even though the drug is still considered experimental, there are so many people already benefiting from it. The guide above should help you leverage PRL-8-53  benefits.


PRL-8-53 (51352-87-5) Reference

  1. Hansl NR. A novel spasmolytic and CNS active agent 3-(2-benzylmethylamino ethyl) benzoic acid methyl ester hydrochloride. Experientia. (1974)
  2. Hansl NR, Mead BT. PRL-8-53: enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent. Psychopharmacology (Berl). (1978)
  3. Hansl NR. (1974). A novel spasmolytic and CNS active agent: 3-(2-benzylmethylamino ethyl) benzoic acid methyl ester hydrochloride. Experientia, 30(3): 271–272.


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