Pyridoxal HCL Powder (65-22-5)

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Category: SKU: N/A

Name:Pyridoxal HCL

CAS:65-22-5

Molecular Formula: C8H10ClNO3

STORAGE:Store in a cool and dry place. Keep away from direct sunlight and heat.

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Pyridoxal HCL Powder (65-22-5) video

 

Pyridoxal HCL Powder Base Information

Name Pyridoxal HCL
CAS 65-22-5
Purity 98%
Chemical name Pyridoxal hydrochloride
Synonyms 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride / Pyridoxal HCL
Molecular Formula C8H10ClNO3
Molecular Weight 203.622
Melting Point 173 °C (dec.) (lit.)
InChI Key FCHXJFJNDJXENQ-UHFFFAOYSA-N
Form powder
Appearance white to off-white
Half Life /
Solubility water: soluble 50 mg/mL, clear, colorless to light greenish-yellow
Storage Condition −20°C
Application Pyridoxal hydrochloride powder(Pyridoxal HCL powder) has been used as a calibrant for liquid chromatography of food samples. It has also been used as a component of arginine decarboxylase broth[3] and lysine decarboxylase broth (LDB) for culturing lactic acid bacteria (LAB) andfood-borne pathogens (FBP), respectively.

For the labeling of amino acids and their detection in picomolar amounts; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate

Testing Document Available

 

Pyridoxal HCL Powder General Description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of certain enzymes. PLP is also the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal and pyridoxamine. This co-factor acts as an electron sink to stabilize carbanionic intermediates in both substitution and elimination reactions involving aminated compounds.

PLP acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.

PLP plays a role in the conversion of levodopa into dopamine, facilitates the conversion of the excitatory neurotransmitter glutamate to the inhibitory neurotransmitter GABA, and allows SAM to be decarboxylated to form propylamine, which is a precursor to polyamines.

 

Pyridoxal HCL Powder Mechanism Of Action

Pyridoxal HCL powder interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.

 

Pyridoxal HCL Powder (65-22-5) Application

Pyridoxal HCL powder is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements. Pyridoxal is one of the three natural forms of vitamin B6, along with pyridoxamine and pyridoxine. All of these forms are converted in the human body into a single biologically active form, Pyridoxal 5-phosphate (P991715). Green plants are a natural source of Pyridoxal, and its deficiency in the human body can lead to serious complications such as epilepsy and seizures.

 

Pyridoxal HCL Powder (65-22-5) Reference

  • Kanchanadevi, A.; Ramesh, R.; Semeril, D. Synthesis of Ru(II) pyridoxal thiosemicarbazone complex and its catalytic application to one-pot conversion of aldehydes to primary amides. Inorg. Chem. Commun. 2015, 56, 116-119.
  • Hassan, B.; Shireen, A.; Muraleedharan, K.; Mujeeb, V. M. A. Virtual screening of molecular properties of chitosan and derivatives in search for druggable molecules. Int. J. Biol. Macromol. 2015, 74, 392-396.
  • Osswald, H., et al., 1987. The influence of sodium ascorbate, menadione sodium bisulfite or pyridoxal hydrochloride on the toxic and antineoplastic action of N-methylformamide in P 388 leukemia or M 5076 sarcoma in mice. Toxicology. 43(2): 183-91. PMID: 3810660
  • Reimer, L G., et al., 1983. Effect of pyridoxal on growth of nutritionally variant streptococci and other bacteria on sheep blood agar. Diagnostic microbiology and infectious disease. 1(4): 273-5. PMID: 6667606

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