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S.O.D. Superoxide Dismutase powder (9054-89-1)

Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide(H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2−).

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Category: Supplements

Superoxide Dismutase Powder Chemical Base Information

Name	Superoxide Dismutase Powder
CAS	9054-89-1
Specification	Plant extract SOD 10,000iu/g (corn germ) Plant extract SOD 20,000iu/g (corn germ) Plant extract SOD 50,000iu/g (corn germ)
Chemical name	Superoxide dismutase
Synonyms	SOD; SOD1; SOD-3; hrSOD; EC-SOD; rh-SOD1; Cuprein; ORGOTEIN; Ontosein; Ormetein
Molecular Formula	/
Molecular Weight	/
Boling Point	/
InChI Key	/
Form	Solid
Appearance	White or Light Blue Crystalline Powder
Half Life	N/A
Solubility	Dissolves readily at 5 mg/mL in 0.05 M potassium phosphate buffer, pH 7.8, containing 0.1 mM EDTA.
Storage Condition	–20 °C
Application	As nutrition and health care products, oral liquid, cosmetic ingredient additives dosage:
Testing Document	Available

S.O.D. Superoxide Dismutase powder 9054-89-1 General Description

Superoxide dismutase (SOD) is an enzyme found in all living cells. An enzyme is a substance that speeds up certain chemical reactions in the body.

Superoxide dismutase helps break down potentially harmful oxygen molecules in cells. This might prevent damage to tissues. Some superoxide dismutase products are made from cows. Others are made from melons or created in a lab.

People use superoxide dismutase for osteoarthritis, rheumatoid arthritis (RA), heart attack, pneumonia, stress, and many other conditions, but there is no good scientific evidence to support most of these uses.

S.O.D. Superoxide Dismutase powder 9054-89-1 Mechanism Of Action

Superoxide dismutase is an enzyme that helps break down potentially harmful oxygen molecules in cells, which might prevent damage to tissues. It is being researched to see if it can help conditions where oxygen molecules are believed to play a role in disease.

S.O.D. Superoxide Dismutase powder 9054-89-1 Application

Since human skin is directly in contact with oxygen, it can cause skin aging and damage. The effect of SOD on protecting the skin and preventing oxidation is outstanding. A lot of cosmetics and health care products have added SOD, which has certain effects on skin care, anti-aging and prevention of age spots.

The formation and elimination of free radicals in normal healthy organisms is in a dynamic equilibrium, but with the increase of age, the content of SOD in the body shows a downward trend. Correspondingly, the growth of free radicals will destroy the balance of the body and cause various kinds of disease. Therefore, maintaining an appropriate amount of SOD in the body is an effective way to maintain health and delay aging. According to this principle, SOD, one of the free radical scavengers, has been used in clinical treatment research and has achieved certain effects.

Like other oxidants, SOD can be used as an antioxidant for canned foods, juices, beer, etc., to prevent food deterioration and spoilage caused by peroxidase, and as a good preservative for fruits and vegetables. In order to expand the application range of SOD in food, it is necessary to enhance the stability of SOD. It is necessary to chemically modify SOD and select substances with no toxic side effects as modifiers, such as heparin compounds, chondroitin sulfate, and fatty acids. Among them, SOD modified by glass acid and lauric acid has been put into commercial production. Studies have shown that the preparation of SOD liposomes not only enhances stability, but also promotes the absorption of human skin.

The overexpression of SOD in transgenic plants can increase the resistance of plants to stress, and the overexpression of Mn-SOD gene can increase the tolerance of transgenic plants to oxygen stress. By genetic engineering, increasing the expression of SOD in plants can greatly enhance the stress resistance of plants.

S.O.D. Superoxide Dismutase powder 9054-89-1 More research

More research is needed to fully understand potential superoxide dismutase side effects when supplements are used to treat certain medical conditions. Some researchers have expressed concern about the risks of consuming SOD supplements made from animal sources because the animal may be sick or diseased.

Some mild side effects that have been reported after SOD intravenous administration are pain and irritation at the injection site.

It’s important to consult with your health care professional before using SOD supplements to improve symptoms of any medical condition. Researchers aren’t sure that antioxidant enzymes from animal sources are safe for regular and long-term consumption.

There also isn’t enough evidence to recommend SOD for women who are pregnant or breastfeeding, so people in these circumstances should use caution unless advised otherwise by their health care professionals.

Reference

1.Cerqueira M D, El R S. Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Therapeutic Perspectives. Oxidative Medicine and Cellular Longevity, 2011,(2011-11-23), 2011, 2011(3).

2.Hayyan M, Hashim MA, Al Nashef IM (2016). “Superoxide Ion: Generation and Chemical Implications”. Chem. Rev. 116 (5): 3029–3085.

3.Alscher RG, Erturk N, Heath LS (May 2002). “Role of superoxide dismutases (SODs) in controlling oxidative stress in plants”. Journal of Experimental Botany. 53 (372): 1331–41.