CBD Isolate Powder

CBD isolate is a crystalline solid or powder that contains 99% pure CBD. CBD Isolate unlike full-spectrum CBD products, CBD Isolate dose not contact any THC-the psychoactive component of cannabis(THC free). So CBD isolate pure powder is a good option for those who would like to try CBD, but who cannot or do not want to ingest any tetrahydrocannabinol (THC), which is the active ingredient in cannabis. Most other CBD products contain at least a small percentage of THC.

CBD isolate powder is used in edibles, pain relief ointments and is the preferred form of CBD for dabbing.

Wisepowder has the capability to produce and supply large quantity. All production under cGMP condition and strict quality control system, all testing documents and sample available.

Chemical Base Information

Name CBD Isolate
CAS 13956-29-1
Purity 99% Isolate / Extrapure Isolate (CBD≥99.5%)
Chemical name CANNABIDIOL
Synonyms CBD; C07578; CBD oil; CBD crystal; CANNABIDIOL;CBD Isolate; (1r-trans)-;CBD powder 99%; CBD,CANNABIDIOL; (-)-CANNABIDIOL
Molecular Formula C21H30O2
Molecular Weight 314.46
Melting Point 62-63°C
Form Solid
Appearance White to light yellow crystalline powder
Half Life 18–32 hours
Solubility Soluble in oil, extremely soluble in ethanol and methanol, insoluble in water
Storage Condition Room temperature, keep dry and away from light
Application For scientific research purposes only, or as raw materials for downstream product development, or for sale in legitimate countries and regions abroad. Please note these products should not be directly consumed or used for clinical treatment in China mainland
Testing Document Available


What Is CBD Isolate Powder 13956-29-1

CBD isolate is a crystalline solid or powder that contains 99% pure CBD. It is Cannabidiol in its purest state currently available on the market today. CBD Isolate is 99% pure, white crystalline that is ground up into powdered form. Therefore, it is 100% THC free and free of other plant compounds including terpenes and other cannabinoids. It contains no psychoactive components.CBD Isolate powder may influence several bodily functions, including:




pain perception

inflammation levels


How Does CBD Isolate Powder Work/The Mechanism Of CBD Isolate Powder

CBD Isolate have good effects on body is because CBD works by acting on the cannabinoid receptors in the human body. These receptors exist because the human body produces its own cannabinoids.

Researchers believe that CBD does not attach directly to these receptors, but that it influences them in some way. As a result of this receptor activation, CBD exerts its effects on the human body.


CBD Isolate Powder History

Efforts to isolate the active ingredients in cannabis were made in the 19th century. Cannabidiol was studied in 1940 from Minnesota wild hemp and Egyptian Cannabis indica resin. The chemical formula of CBD was proposed from a method for isolating it from wild hemp. Its structure and stereochemistry were determined in 1963.


Why Buy CBD Isolate Powder/What Are The Benefits Of CBD Isolate Powder?

1. Anxiety, Depression, and Stress

Several studies indicate that CBD Isolate powder has anti-anxiety effects. It likely works by changing the way the brain responds to the chemical serotonin.One 2011 study looked into CBD’s effects on people with SAD (seasonal affective disorder) . SAD is a type of depression that sufferers experience through the winter months when it’s cold, wet, and dark.Another 2019 study suggests that CBD significantly decreased anxiety in teenagers with social anxiety.


2. Pain Relief

People often use CBD Isolate powder to treat a variety of inflammatory conditions and types of pain, including:

arthritis pain

cancer pain

chronic back pain


neuropathic pain

While CBD isolate may provide pain relief, research indicates that a full-spectrum CBD product may be even more effective because cannabidiol acts synergistically with THC to boost its analgesic effects.


3. Inflammation Relief

Studies show that CBD Isolate powder has anti-inflammatory properties.

Research has discovered that CBD can relieve inflammation and pain in people with inflammatory conditions when used in topical and ingested forms.

With the potential to relieve arthritis, psoriasis, dermatitis, acne, and much more, the anti-inflammatory benefits of CBD are valuable to a wide group of people.


4. Alleviate Nausea

There’s limited scientific evidence that proves CBD Isolate powder is an effective anti-nausea drug. However, there is a lot of anecdotal evidence to suggest it’s effective.

Some cancer patients use CBD to reduce nausea and other side effects of cancer treatments and therapies with excellent results.

One study from 2011 suggests CBD can help with nausea due to its interaction with serotonin receptors . The study involved animal testing and found that their nausea response was greatly reduced when CBD was administered to rats.


5. Cancer Treatment

Research into the effects of CBD on cancer growth is also in the early stages. However, some animal studies do indicate that it might prevent the growth of cancer cells.

The National Cancer InstituteTrusted Source indicates that CBD may alleviate some cancer symptoms and side effects of cancer treatment (including nausea and vomiting).

However, the Institute does not endorse any form of cannabis as a treatment due to insufficient research.

The benefits of CBD Isolate powder goes on….


6. THC Free

Pure CBD is 100 percent THC-free for those who must or prefer to not have any trace amounts of THC in their system. so there’s no need to worry about THC possibly entering your system and showing up on a potential drug test. Although it’s highly unlikely, trace amounts of THC found in hemp-derived CBD oil can theoretically cause a positive drug screening result.


7. Easy Usage

Isolate is relatively taste-free, so it’s a great way to add CBD to your own custom formulation. How to use CBD Powder? CBD Powder can be consumed in a variety of ways: CBD powder is most popularly used by mixing it into edibles and CBD oils or CBD capsules. CBD can be smoked or vaporized. CBD powder is often used as a substitute to CBD oils, giving the user the ability to control their dosage.


8. Easy Dosage

CBD powder is easily measurable as there’s nothing else to account for aside from the pure CBD. With other CBD-based products, such as broad-spectrum and full-spectrum CBD oil, the cannabinoid is mixed with other cannabinoids, making it more difficult at times to quantify the exact amount of CBD that is being consumed.


9. Other Benefits Of CBD Isolate Powder

-boosting the immune system (immune-modulating)

-counteracting the formation of tumors (anti-tumorigenic)

-fighting inflammation (anti-inflammatory)

-preventing vomiting (antiemetic)

-recovery or regeneration of the nervous system (neuroprotective)

-reducing or preventing anxiety (anti-anxiety)

-reducing or preventing seizures (anticonvulsant)

-relieving pain (analgesic)


10. Effects on THC

CBD is thought to have an attenuating effect on THC, so it can also be used to decrease or balance out THC effects.


How To Make CBD Isolate Powder?

CBD works by binding with the endocannabinoid receptors in the body’s nervous system optimizes functions regulated by the endocannabinoid system. For this reason, CBD possesses multiple uses for overall wellness. The exact reason why CBD isolates and other CBD products are so helpful is still being studied by researchers and scientists.

Those that need to refrain from consuming THC because of their age, the legality in their state, or because of employer drug testing, CBD isolate is a practical alternative to full spectrum oils, which contain trace amounts of THC.

CBD powder has so many good benefits, how to make CBD Isolate powder?

There are various processes used to produce CBD isolate from industrial hemp extracts, such as supercritical carbon dioxide (CO2) or ethanol-based extractions. The same extraction methods can also be used as a starting point for the production of THC isolate as well, but typically with marijuana plants instead of industrial hemp. To create an isolate, a number of components are removed from the plant, including other cannabinoids, terpenes, and flavonoids, as well as fats, lipids, and other compounds. After that, the CBD compound is separated from the rest of the extraction through a series of chemical washing and separation processes.

Once all of the impurities and solvents are stripped away, you’re left with 99% pure CBD crystalline.


How To Use CBD Isolate Powder?

1. Sublingual

To take CBD isolate powder sublingually is one of the most effective ways to consume CBD.

By this method, CBD is absorbed by the mucous membranes and delivered directly to the bloodstream, bypassing the digestive system and liver to provide more immediate and effective relief. The powder is odorless and has a mild, cannabis flavor.


2. Apply to skin

Mix the CBD isolate with moisturizing oils or lotions and apply it to the area of your skin you’d like to treat.

Applying CBD isolate to your skin allows you to use your preferred topical product while enjoying an extra kick of the isolate and maintaining full control over the CBD dosage. It’s also fun to experiment and make your own DIY topical, whether lotion, salve, or cream.


3. Oral-put into capsule or your foods

Measure out the CBD isolate powder at the dosage you prefer and put into capsules. You can also mix CBD isolate with a variety of ingredients to create CBD-infused food and drinks.What’s more, buying CBD isolate powder in bulk can make this method one of the most economical. However, because CBD is not absorbed very well by the gastrointestinal tract, it has a low oral bioavailability. In order to increase bioavailability, CBD isolate can be added to carrier oils, such as MCT oil, to increase its chances of permeating the gastrointestinal system and reaching the bloodstream


4. Vape or dab it.

Vaping CBD isolate won’t get you high, but it will enable you to enjoy the effects of CBD quickly. CBD isolate can be mixed with terpenes to create homemade CBD concentrates, or it can be dabbed using a concentrate vaporizer or dry herb vaporizer.


What Are The Side Effects Of CBD Isolate Powder?

CBD isolate is generally a low-risk substance, especially as it does not contain THC. However, in some people, it may cause adverse reactions that include:

an increase or decrease in appetite



weight loss or weight gain



CBD can also interact with some prescription or over-the-counter medications, so always talk to a doctor before using CBD or other cannabis products.

One study in mice indicated that CBD might also increase the risk of liver toxicity if taken in significant quantities. Anyone considering using CBD should talk to their doctor or one who specializes in CBD to evaluate their risk.


CBD Isolate Vs Full and Broad Spectrum CBD, Which One Is Beeter?

Research suggests that full- and broad spectrum CBD is a more valuable treatment for a wider range of health conditions.

It’s believed that CBD is more effective when consumed alongside other cannabinoids. A full cannabinoid profile is more efficient than singular cannabinoid extractions. This phenomenon is known as the entourage effect.

That being said, CBD isolates still have excellent potential in the health space.

Many studies have been done on pure CBD isolates, and although the conclusion that full-spectrum oils are better, isolates are still effective in treating some conditions.

You may prefer to use a CBD isolate because you want to avoid THC and other cannabinoids entirely. Perhaps you react badly to some other cannabinoids or would prefer to steer clear of full-spectrum products for other reasons.

There are pros and cons to using CBD isolates, just as there are for full- and broad spectrum products.


CBD Isolate: Pros & Cons


Contains only CBD

Plenty of product variety

No risk of showing up on a drug test

Suitable for people with adverse reactions to other cannabinoids

Raw oil tastes less than full & broad spectrum CBD oil


No entourage effect

May not be a suitable treatment for some condition


Full-Spectrum CBD: Pros & Cons


Full entourage effect

Wide product variety

Can treat a range of health conditions


May show up on drug tests as it contains trace amounts of THC

Not suitable for people that react to certain cannabinoids or terpenes

Raw oil has a taste that’s unappealing to some


Broad Spectrum CBD: Pros & Cons


Has the entourage effect to some extent (minus the THC)

Wide product variety

Effective for multiple health issues

Doesn’t show up on drug tests


Doesn’t have the full entourage effect

Raw oil has an unappealing taste to some


How Much CBD Isolate Dosage Should I Take?

How much CBD isolate dosage you should take is depends, it is different for everybody.  The dose of CBD isolate can change depends on many factors include:

– individual metabolism,

-the strength of the CBD products you are using

-your body size and weight

-your sensitivity and tolerance to CBD

-the severity of the condition you are treating

Start low and increase the dose until you find what works best for you. The common dosage of CBD is 20-40mg. Even with same dose of CBD, it is common for different people respond very differently to it.


Frequently Ask Questions About CBD Isolate Powder

How Do You Use CBD Isolate Powder?

CBD Isolate Powder is CBD in an extremely fine powder form. CBD Powder is CBD Crystals in their purest form. CBD Powder has many uses, including mixing with e-liquids in order to vape CBD. CBD Powder can also be used to make CBD edibles, CBD topicals and CBD tinctures by simply mixing CBD powder with a carrier oil, like coconut or hemp seed oil.


What Does CBD Make You Fee?

Instead of getting you stoned, CBD makes you feel relaxed and calm without producing any mind-altering effects. You may be surprised to learn that your body produces substances very similar to cannabinoids, known as endocannabinoids, on its own.


Is CBD Isolate Powder Legal?

If your purified CBD comes from hemp plants, it is federally legal, but if it comes from a marijuana plant, it is illegal.


What Is The Best Effective Method To Use CBD Isoate powder?

Most Efficient Method of Consumption – Sublingually-administered CBD is the most direct and efficient form of CBD consumption, having the highest and fastest absorption rate of cannabidiol.


How To Make CBD Isolate Powder Into Oil?

CBD oil can be made from CBD isolate by combining it with a carrier oil like MCT oil, grapeseed oil or olive oil. MCT oil is the most popular carrier oil used for formulating CBD oil from isolate.


How Can You Tell High Quality CBD Isolate Powder?

A reputable CBD product will come with a COA. That means it’s been tested by laboratory prove it’s purity. For powerful CBD isolate powder manufacturers, they can provide other offical professional testing result to prove the quality, such as HPLC,NMR, not all factory can provide such kinds of testing documents, as they need professional technology team and equipments.


Is CBD Same As CBD Isolate?

CBD is cannabidiol, a phytocannabinoid found in cannabis plants. CBD isolate is CBD that has been isolated from all other plant material through a process of extraction and refining. CBD isolate is available in crystal or powder form.


Is CBD isolate Better Than full-spectrum CBD?

It depends on who you ask and why they are using CBD. Isolate is best for avoiding any possible trace of THC while full-spectrum may confer the additional benefits of other cannabinoids and terpenes via the entourage effect.


How To Buy CBD Isolate Powder Online?

CBD isolate, which doesn’t contain THC, is a more pure form of CBD. Wisepowder is wholesale the 99% pure CBD Isolate powder, our Wholesale CBD Isolate is the best  powder in the industry.  When buy CBD isolate powder in bulk online, check to make sure it is undergone lab inspection and has a Certificate of Analysis(COA) available to prove it. There are too many CBD isolate powder suppliers in the market, the powerful CBD isolate powder manufacturer will have the professional technology and equipments, strict quality system to ensure the products quality.