Compound 7P powder (1890208-58-8)

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Name:Compound 7P

CAS:1890208-58-8

Molecular Formula:  C22H23N3O5S

STORAGE:Store in a cool and dry place. Keep away from direct sunlight and heat.

Compound 7P powder (1890208-58-8) video

 

Compound 7P powder Base Information

Name Compound 7P powder
CAS 1890208-58-8
Purity 98%
Chemical name 2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide
Synonyms Compound 7P

CHEMBL3824120

Molecular Formula C22H23N3O5S
Molecular Weight 441.5 g/mol
Melting Point About 159℃
InChI Key NAXWKPFXCOBXLE-UHFFFAOYSA-N
Form Solid
Appearance White
Half Life 1-2h
Solubility Soluble in ethyl acetate,dichloromethan;

Slightly soluble in methanol;insoluble in

water

Storage Condition in a dry place, out of light.
Application Compound 7p was developed as one in series of compounds with the aim of identifying dual-acting thromboxane receptor antagonist/synthase inhibitors .
Testing Document Available

 

Compound 7P powder General Description

Raw Compound 7P powder which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina.

In an animal model of optic nerve injury, Raw Compound 7P was shown to induce growth of gap-43 positive axons, indicating that the in vitro neurite outgrowth activity of Raw Compound 7P translates into stimulation of axon regeneration in vivo.

 

Compound 7P (1890208-58-8) History

Compound 7p was developed as one in series of compounds with the aim of identifying dual-acting thromboxane receptor antagonist/synthase inhibitors .

In fact compound 7p shows selectivity for prostaglandin I2 synthase (PTGIS , CYP8A1) over thromboxane synthase (CYP5A1) .

 

Compound 7P (1890208-58-8) Benefits

  1. Repare the danage head nerve
  2. Promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina.

 

Compound 7P (1890208-58-8) More research

Further optimization of compound 7p and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies.

 

Compound 7P (1890208-58-8) Reference

  • Design, synthesis and molecular docking of thiazolidinedione based benzene sulphonamide derivatives containing pyrazole core as potential anti-diabetic agents. Naim MJ, Alam O, Alam MJ, Hassan MQ, Siddiqui N, Naidu VGM, Alam MI. Bioorg Chem. 2018 Feb;76:98-112. doi: 10.1016/j.bioorg.2017.11.010. Epub 2017 Nov 16. PMID: 29169079
  • Novel 1,3,5-triazine derivatives exert potent anti-cervical cancer effects by modulating Bax, Bcl2 and Caspases expression. Wang X, Yi Y, Lv Q, Zhang J, Wu K, Wu W, Zhang W. Chem Biol Drug Des. 2018 Mar;91(3):728-734. doi: 10.1111/cbdd.13133. Epub 2017 Nov 15. PMID: 29068538
  • Potential anti-cancer activity of 7-O-pentyl quercetin: Efficient, membrane-targeted kinase inhibition and pro-oxidant effect. Sassi N, Mattarei A, Espina V, Liotta L, Zoratti M, Paradisi C, Biasutto L. Pharmacol Res. 2017 Oct;124:9-19. doi: 10.1016/j.phrs.2017.07.016. Epub 2017 Jul 17. PMID: 28728925
  • Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells. Bommagani S, Ponder J, Penthala NR, Janganati V, Jordan CT, Borrelli MJ, Crooks PA. Eur J Med Chem. 2017 Aug 18;136:393-405. doi: 10.1016/j.ejmech.2017.05.031. Epub 2017 May 11. PMID: 28525840 Free PMC Article
  • Best Nootropic Stack Guide: Everything You Need To Know [5 Years Experience]

 

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