Urolithin A Powder 1143-70-0

Free shipping for order over US$249 (USA and Asia)
Free shipping for order over US$349 (Europe)
5-10 hours(in business day) fast shipping
Only 14 left! 71 people are viewing this and 60 people have it in their cart.
No your quantity? Click here
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.
Category: SKU: N/A

Name:Urolithin A


Molecular Formula:C13H8O4

STORAGE:Store in a cool and dry place. Keep away from direct sunlight and heat.

How To Place Order?
[1]. Choose quantity you need, then add to cart

[2]. Proceed to check out

[3]. Fill in your detail information, the *is required, choose your payment method. There are different payment methods include:
-Direct Bank Transfer
-Coinpayments: Bitcoin,Ether,USDT
Then click “Place order”
Tips: the email address must correct, the tracking information will keep update through email notice

[4]. If choose “Coinpayment”, after click “Place order”, then will show as below to pay

[5]. If Choose “Direct Bank Transfer”, after click “Place order”, then will show as below, will appear the bank account details, after make bank transfer (please use your order number as the reference), send a bank slip to us

[6]. Payment confirmed
[7]. Parcel send out about 5-10 hours (in business day)
[8]. Tracking number provided
[9]. Parcel arrived
[10]. Re-order

Urolithin A Powder Base Information

Name Urolithin A Powder
CAS 1143-70-0
Purity 98%
Chemical name 3,8-Dihydroxybenzo[c]chromen-6-one
Synonyms 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one; 3,8-DIHYDROXYDIBENZO-(B,D)PYRAN-6-ONE; 3, 8-Dihydroxy-6H-benzo[c]chromen-6-one; Castoreum pigment I; Urolithin A; 6H-Dibenzo(B,D)pyran-6-one, 3,8-dihydroxy-; 3,8-dihydroxy-6H-dibenzopyran-6-one); urolithin-A(UA;3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one
Molecular Formula C13H8O4
Molecular Weight 228.2
Melting Point >300 °C
Form solid
Appearance Light Yellow powder
Half Life
Solubility Soluble in DMSO (3 mg/mL).
Storage Condition Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Application Urolithin A is a metabolite of ellagitannin; Pharmaceutical Intermediates
Testing Document Available


Urolithin A Powder 1143-70-0 General Description

Urolithin A powder is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria and is an inducer of mitophagy. Urolithin A shifts mitochondria from CI- to CII-driven respiration, extends lifespan and improves muscle function. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. Its precursors – ellagic acids and ellagitannins – are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts. Since the 2000s, urolithin A has been subject of preliminary studies regarding its possible biological effects.

Urolithin A powder can improve the quality and function of mitochondria, and increase the strength and endurance of aging muscles. It is the only natural product that has been proven to restart mitochondrial autophagy and reverse muscle aging.

Urolithins are microflora human metabolites of dietary ellagic acid derivatives,such as ellagitannins. They are produced in the

human gut, and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing food such as

pomegranate, strawberries, red raspberries, walnuts or oak-aged red wine.

During intestinal metabolism by bacteria, ellagitannins and punicalagins are converted to urolithins, which have unknown

biological activity in vivo in humans. Urolithins metabolites of pomegranate juice ellagitannins localize specifically in

the prostate gland, colon, and intestinal tissues of mice.

Ellagitannins exhibit low bioavailability and are transformed in the gut to ellagic acid and its microbiota metabolites.

Urolithins are found in plasma mostly as glucuronides at low concentrations.

Urolithins production is dependent on the gut microbiome enterotype. Individuals producing urolithins show a much higher abundance

of the Clostridium leptum group of Firmicutes phylum than Bacteroides or Prevotella


Urolithin A Powder 1143-70-0 History

In laboratory studies, urolithin A powder was shown to induce mitophagy, which is a selective recycling of mitochondria by autophagy, a process that cleans defective mitochondria following damage or stress, and tends to become less efficient during aging.[14] This effect has been observed in different animal species (mammalian cells, rodents and C. elegans).


Urolithin A Powder 1143-70-0 Application

Urolithin A powder is intended for use as an ingredient in select foods or for special dietary uses in meal replacement products based on its nutritive activity in supporting general mitochondrial health.


Urolithin A Powder 1143-70-0 More research

Urolithin A is not known to be found in any food. It forms as the result of transformation of ellagic acids and ellagitannins by the gut microflora in humans. Ellagic acid itself results from the hydrolysis of ellagitannins in the gut in the presence of water.[citation needed]

Sources of ellagitannins are: pomegranates, nuts, some berries (raspberries, strawberries, blackberries, cloudberries), tea, muscadine grapes, many tropical fruits, and oak-aged wines (table below).

The conversion of the ellagic acids into urolithin A depends on individual microflora composition and can vary significantly.


Urolithin A Powder 1143-70-0 Reference

  1. Paller CJ, Pantuck A, Carducci MA. A review of pomegranate in prostate cancer. Prostate Cancer Prostatic Dis. 2017 Apr 25. doi: 10.1038/pcan.2017.19. [Epub ahead of print] Review. PubMed PMID: 28440320.
  2. Ito H. Metabolites of the ellagitannin geraniin and their antioxidant activities. Planta Med. 2011 Jul;77(11):1110-5. doi: 10.1055/s-0030-1270749. Epub 2011 Feb 3. Review. PubMed PMID: 21294073.
  3. Ishimoto H, et al. In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5901-4.


There are no reviews yet.

Be the first to review “Urolithin A Powder 1143-70-0”

Your email address will not be published. Required fields are marked *


Lost your password?


Your cart is currently empty.